Published in:
01-04-2015 | Editorial
Note of clarification of data in the paper titled X-ray repair cross-complementing group 1 Arg194Trp polymorphism is associated with increased risk of lung cancer in Chinese Han population
Authors:
Haiyan Yang, Ruo Feng, Haiyu Wang, Yadong Wang
Published in:
Tumor Biology
|
Issue 4/2015
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Excerpt
We read with great interest the paper titled “X-ray repair cross-complementing group 1 Arg194Trp polymorphism is associated with increased risk of lung cancer in Chinese Han population” published in
Tumor Biol. 2013, 34: 2611–2615 [
1]. Wu et al. performed a meta-analysis to investigate the association between X-ray repair cross-complementing group 1 (XRCC1) Arg194Trp polymorphism and lung cancer risk in Chinese Han population on the basis of 12 case-control studies with 4385 cases and 4545 controls. The authors found that XRCC1 Arg194Trp polymorphism was associated with increased risk of lung cancer in Chinese Han population under three main models (allele contrast model, odds ratio (OR) = 1.12, 95 % confidence interval (CI) 1.00–1.26,
P = 0.049; homozygote model, OR = 1.27, 95 % CI 1.09–1.48,
P = 0.003; recessive model, OR = 1.26, 95 % CI 1.09–1.46,
P = 0.003) when all eligible studies were pooled into meta-analysis. It is an interesting study. …