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Indian Journal of Hematology and Blood Transfusion

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01-09-2014 | Case Report

Noninvasive Diagnosis and Continuous Monitoring of Local Anesthetic-Induced Methemoglobinemia in a Neonate

Authors: Ozgun Uygur, Sefika Esen, Sema Tanriverdi, Ozge A. Koroglu, Mehmet Yalaz, Nilgun Kultursay

Published in: Indian Journal of Hematology and Blood Transfusion | Special Issue 1/2014

Excerpt

Methemoglobin (MetHb) has an oxidized ferric iron (Fe⁺³) instead of regular reduced ferrous form (Fe⁺²) of normal hemoglobin [1]. This structural change of MetHb is responsible for its inability to bind oxygen [1, 2]. …

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Denshaw-Burke M, Curran AL et al (2013) Methemoglobinemia. http://emedicine.medscape.com/article/204178-overview

Osterhoudt KC (2001) Methemoglobinemia. In: Ford M, Delaney K, Ling L, Erickson T (eds) Ford: clinical toxicology, 1st edn. W.B. Saunders Company, Philadelphia, pp 211–217

Tetzlaff JE (2000) The pharmacology of local anesthetics. Anesthesiol Clin N Am 18:213–233CrossRef

Duncan PG, Kobrinsky N (1983) Prilocaine-induced methemoglobinemia in a newborn infant. Anesthesiology 59:75–76PubMedCrossRef

Kumar AR, Dunn N, Naqvi M (1997) Methemoglobinemia associated with a prilocaine-lidocaine cream. Clin Pediatr 36:239–240CrossRef

Goldstein MR, Saesim D, Macknet M et al (2008) Do pulse CO-oximeter measures of Spmet and SpO2 correlate with blood gas CO-oximetry in neonates? Anestesiology 109: A1218 poster

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Title: Noninvasive Diagnosis and Continuous Monitoring of Local Anesthetic-Induced Methemoglobinemia in a Neonate
Authors: Ozgun Uygur
Sefika Esen
Sema Tanriverdi
Ozge A. Koroglu
Mehmet Yalaz
Nilgun Kultursay
Publication date: 01-09-2014
Publisher: Springer India
Published in: Indian Journal of Hematology and Blood Transfusion / Issue Special Issue 1/2014
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI: https://doi.org/10.1007/s12288-013-0315-7

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