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01-09-2017 | Original Article

Noninvasive assessment of cutaneous alterations in mice exposed to whole body gamma irradiation using optical imaging techniques

Authors: P. Sharma, K. Sahu, P. K. Kushwaha, S. Kumar, M. K. Swami, J. Kumawat, H. S. Patel, S. Kher, P. K. Sahani, G. Haridas, P. K. Gupta

Published in: Lasers in Medical Science | Issue 7/2017

Abstract

We report the results of a study carried out to investigate the potential of optical techniques such as optical coherence tomography, Mueller matrix spectroscopy, and cross-polarization imaging for noninvasive monitoring of the ionizing radiation exposure-induced alterations in cutaneous tissue of mice. Radiation dose-dependent changes were observed in tissue microvasculature and tissue optical parameters like retardance and depolarization as early as 1 h post radiation exposure. Results suggest that these optical techniques may allow early detection of radiation dose-dependent alterations which could help in screening of population exposed to radiation.

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Title: Noninvasive assessment of cutaneous alterations in mice exposed to whole body gamma irradiation using optical imaging techniques
Authors: P. Sharma
K. Sahu
P. K. Kushwaha
S. Kumar
M. K. Swami
J. Kumawat
H. S. Patel
S. Kher
P. K. Sahani
G. Haridas
P. K. Gupta
Publication date: 01-09-2017
Publisher: Springer London
Published in: Lasers in Medical Science / Issue 7/2017
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-017-2276-9

At a glance: The STEP trials

Springer Medicine

Noninvasive assessment of cutaneous alterations in mice exposed to whole body gamma irradiation using optical imaging techniques

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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