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International Ophthalmology

Published in:

01-04-2008 | Original Paper

Non-infectious endophthalmitis associated with trypan blue use in cataract surgery

Authors: Lihteh Wu, Roberto Velasquez, Olga Montoya

Published in: International Ophthalmology | Issue 2/2008

Abstract

Background

The visualization of the anterior lens capsule is greatly enhanced by trypan blue staining facilitating the creation of a continuous curvilinear capsulorhexis. Trypan blue has been deemed safe in this setting.

Methods

We report the findings and management of a retrospective interventional case series comprising three eyes that developed non-infectious endophthalmitis following routine trypan blue staining of the anterior lens capsule with the same batch of Vission (0.6 mg/ml) during uncomplicated small incision phacoemulsification of 17 consecutive eyes.

Results

On post-op day 1, 18% had an increased cellular response in the anterior chamber and anterior vitreous precluding fundus visualization, 12% had a hypopyon. Initial visual acuity (VA) ranged from hand motions to light perception. Eyes were initially managed with topical and oral steroids. Two eyes underwent vitrectomy. Vitreous cultures were all negative. One eye had a repeat vitrectomy to remove an epiretinal membrane. Final VA achieved was 20/80, 20/20 and 20/20.

Conclusion

Trypan blue may be associated with severe intraocular inflammation.

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Title: Non-infectious endophthalmitis associated with trypan blue use in cataract surgery
Authors: Lihteh Wu
Roberto Velasquez
Olga Montoya
Publication date: 01-04-2008
Publisher: Springer Netherlands
Published in: International Ophthalmology / Issue 2/2008
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-007-9119-9

At a glance: The STEP trials

Springer Medicine

Non-infectious endophthalmitis associated with trypan blue use in cataract surgery

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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