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Published in: European Journal of Pediatrics 4/2010

01-04-2010 | Short Report

Non-accidental chlorpyrifos poisoning—an unusual cause of profound unconsciousness

Authors: Jiun-Chang Lee, Kuang-Lin Lin, Jainn-Jim Lin, Shao-Hsuan Hsia, Chang-Teng Wu

Published in: European Journal of Pediatrics | Issue 4/2010

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Abstract

Chlorpyrifos is an organophosphorus anticholinesterase insecticide, and organophosphate intoxication can induce symptoms such as miosis, urination, diarrhea, diaphoresis, lacrimation, excitation of central nervous system, salivation, and consciousness disturbance (MUDDLES). Although accidental poisoning of children with drugs and chemicals is a common cause for consciousness disturbance in children, the possibility of deliberate poisoning is rarely considered. We report on a healthy 5-year 6-month-old boy with recurrent organophosphate intoxication. Reports of chlorpyrifos intoxication in children are quite rare. This case report demonstrates decision-making process and how to disclose deliberate chlorpyrifos poisoning of the toddler by the stepmother, another example of Munchausen syndrome by proxy.
Literature
1.
go back to reference Coye MJ, Barnett PG, Midtling JE et al (1987) Clinical confirmation of organophosphate poisoning by serial cholinesterase analyses. Arch Intern Med 147:438–442CrossRefPubMed Coye MJ, Barnett PG, Midtling JE et al (1987) Clinical confirmation of organophosphate poisoning by serial cholinesterase analyses. Arch Intern Med 147:438–442CrossRefPubMed
2.
go back to reference Johnson MK (1993) Mechanisms of and biomarkers for acute and delayed neuropathic effects of organophosphorus esters, NATO ASI series Series A. Life sciences (USA) 250:169–182 Johnson MK (1993) Mechanisms of and biomarkers for acute and delayed neuropathic effects of organophosphorus esters, NATO ASI series Series A. Life sciences (USA) 250:169–182
3.
go back to reference McClure RJ, Davis PM, Meadow SR et al (1996) Epidemiology of Munchausen syndrome by proxy, non-accidental poisoning, and non-accidental suffocation. Arch Dis Child 75:57–61CrossRefPubMed McClure RJ, Davis PM, Meadow SR et al (1996) Epidemiology of Munchausen syndrome by proxy, non-accidental poisoning, and non-accidental suffocation. Arch Dis Child 75:57–61CrossRefPubMed
4.
go back to reference Meadow R (2002) Different interpretations of Munchausen syndrome by proxy. Child Abuse Negl 26:501–508CrossRefPubMed Meadow R (2002) Different interpretations of Munchausen syndrome by proxy. Child Abuse Negl 26:501–508CrossRefPubMed
5.
go back to reference Muller FO, Hundt HK (1980) Chronic organophosphate poisoning. S Afr Med J 57:344–345PubMed Muller FO, Hundt HK (1980) Chronic organophosphate poisoning. S Afr Med J 57:344–345PubMed
6.
7.
go back to reference Rosenman KD, Guss PS (1997) Prevalence of congenital deficiency in serum cholinesterase. Arch Environ Health 52:42–44CrossRefPubMed Rosenman KD, Guss PS (1997) Prevalence of congenital deficiency in serum cholinesterase. Arch Environ Health 52:42–44CrossRefPubMed
8.
go back to reference Wong TK, Chen C, Liou SC et al (2000) Prolonged neuromuscular block with mivacurium in a patient with cholinesterase deficiency. J Formos Med Assoc 99:656–658PubMed Wong TK, Chen C, Liou SC et al (2000) Prolonged neuromuscular block with mivacurium in a patient with cholinesterase deficiency. J Formos Med Assoc 99:656–658PubMed
Metadata
Title
Non-accidental chlorpyrifos poisoning—an unusual cause of profound unconsciousness
Authors
Jiun-Chang Lee
Kuang-Lin Lin
Jainn-Jim Lin
Shao-Hsuan Hsia
Chang-Teng Wu
Publication date
01-04-2010
Publisher
Springer-Verlag
Published in
European Journal of Pediatrics / Issue 4/2010
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI
https://doi.org/10.1007/s00431-009-1054-5

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