Top

World Journal of Urology

Published in:

01-10-2014 | Topic Paper

Nocturia and its impact on health-related quality of life and health care seeking behaviour in German community-dwelling men aged 50 years or older

Authors: Matthias Oelke, Birgitt Wiese, Richard Berges

Published in: World Journal of Urology | Issue 5/2014

Abstract

Purpose

To evaluate the prevalence of nocturia/nocturnal voiding frequency and its impact on overall physical and mental health status in German community-dwelling men and determine which lower urinary tract symptom (LUTS) is responsible for medical consultations in the 2-year follow-up period.

Methods

A sample of German men aged 50–80 years from a community-dwelling study was chosen for re-evaluation 2 years after initial assessment. Men were clinically investigated and completed the International Prostate Symptom Score, American Urology Association-Symptom Problem Index (AUA-SPI), and the Short-Form Health Survey (SF-12).

Results

In total, 1,562 men were eligible for analysis. Mean nocturnal voiding frequency was 2.3 for all men and increased with ageing. SF-12 data indicated that physical but not mental health status was lower than in the average population. LUTS severity reduced both physical and mental health status (p < 0.001). Clinically relevant nocturia (≥2 voids/night) was present in 43 % of men and reduced both physical and mental health status (p < 0.001), whereas both HRQoL scales were not significantly reduced in men without or only one nocturnal void. In multivariate regression analysis using patient-reported bother (AUA-SPI) from LUTS, only bother from nocturnal voiding was significantly associated with medical consultations in the investigated 2-year follow-up period (odds ratio 2.6; 95 % confidence interval 1.6–4.2; p < 0.001).

Conclusions

Our study confirmed that nocturnal voiding is highly prevalent in community-dwelling men and reduce both physical and mental health status. Bother from nocturnal voiding is the most relevant component of LUTS responsible for medical consultations in German men.

van Kerrebroeck P, Abrams P, Chaikin D, Donovan J, Fonda D, Jackson S et al (2002) The standardisation of terminology in nocturia: report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn 21:179–183PubMedCrossRef

Norgaard JP (2010) The role of nocturia in the quality of life of men with lower urinary tract symptoms. BJU Int 105:1016–1017PubMedCrossRef

Tikkinen KA, Johnson TM 2nd, Tammela TL, Sintonen H, Haukka J, Huhtala H et al (2010) Nocturia frequency, bother, and quality of life: how often is too often? A population-based study in Finland. Eur Urol 57:488–496PubMedCrossRef

Rodrigues P, Meller A, Campagnari JC, Alcantara D, D’Imperio M (2004) International prostate symptom score–IPSS-AUA as discriminat scale in 400 male patients with lower urinary tract symptoms (LUTS). Int Braz J Urol 30:135–141PubMedCrossRef

Barry MJ, Fowler FJ Jr, O’Leary MP, Bruskewitz RC, Holtgrewe HL, Mebust WK (1995) Measuring disease-specific health status in men with benign prostatic hyperplasia: Measurement Committee of The American Urological Association. Med Care 33:AS145–AS155PubMedCrossRef

Ware JE Jr, Kosinski M, Gandek B, Aaronson NK, Apolone G, Bech P et al (1998) The factor structure of the SF-36 health survey in 10 countries: results from the IQOLA Project. International Quality of Life Assessment. J Clin Epidemiol 51:1159–1165PubMedCrossRef

Tengs TO, Wallace A (2000) One thousand health-related quality-of-life estimates. Med Care 38:583–637PubMedCrossRef

Hernandez Fernandez C, Ristol Pont J, Estivill E, Batista Miranda JE, Lopez Aramburu MA (2007) Importance of nocturia and its impact on quality of sleep and quality of life in patient with benign prostatic hyperplasia. Actas Urol Esp 31:262–269PubMedCrossRef

Berges RR, Pientka L, Hofner K, Senge T, Jonas U (2001) Male lower urinary tract symptoms and related health care seeking in Germany. Eur Urol 39:682–687PubMedCrossRef

10.

Berges RR, Pientka L (1999) Management of the BPH syndrome in Germany: who is treated and how? Eur Urol 36(Suppl 3):21–27PubMedCrossRef

11.

Berges R (2008) Epidemiology of benign prostatic syndrome. Associated risks and management data in German men over age 50. Urol A 47:141–148CrossRef

12.

Hutchison A, Farmer R, Verhamme K, Berges R, Navarrete RV. The efficacy of drugs for the treatment of LUTS/BPH, a study in 6 European countries. Eur Urol. 2007;51:207-15; discussion 15-6

13.

Lowe FC, Batista J, Berges R, Chartier-Kastler E, Conti G, Desgrandchamps F et al (2005) Risk factors for disease progression in patients with lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH): a systematic analysis of expert opinion. Prostate Cancer Prostatic Dis 8:206–209PubMedCrossRef

14.

Speakman M, Batista J, Berges R, Chartier-Kastler E, Conti G, Desgrandchamps F et al (2005) Integrating risk profiles for disease progression in the treatment choice for patients with lower urinary tract symptoms/benign prostatic hyperplasia: a combined analysis of external evidence and clinical expertise. Prostate Cancer Prostatic Dis 8:369–374PubMedCrossRef

15.

Berges R, Dreikorn K, Hofner K, Madersbacher S, Michel MC, Muschter R et al (2009) Diagnostic and differential diagnosis of benign prostate syndrome (BPS): guidelines of the German Urologists. Urol A 48:1356–1360 62–64CrossRef

16.

Berges R, Oelke M (2011) Age-stratified normal values for prostate volume, PSA, maximum urinary flow rate, IPSS, and other LUTS/BPH indicators in the German male community-dwelling population aged 50 years or older. World J Urol 29:171–178PubMedCrossRef

17.

Koyanagi T, Artibani W, Correa R, Desgranchamps F, DeReijke TM, Govier F et al (1997) Initial diagnostic evaluation of men with lower urinary tract symptoms. 1989:258–60. In: Benign Prostatic Hyperplasia (BPH), 4th International Consultation on benign prostatic hyperplasia (BPH), Paris, July 2–5, 1997, Griffiths K, Denis L, Khoury S, Cockett ATK, McConnell J, Chatelain C, Murphy G, Yoshida O, Plymbridge Distributors, Plymouth

18.

Ware J Jr, Kosinski M, Keller SD (1996) A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care 34:220–233PubMedCrossRef

19.

Ware JE, Kosinski M, Turner-Bowker DM, Gandek B (2002) How to Score Version 2 of the SF-12v2^® Health Survey (With a Supplement Documenting SF-12^® Health Survey). QualityMetric Incorporated, Lincoln

20.

German Federal Statistics Office (Statistisches Bundesamt) 2012. http://www.bpb.de/wissen/X39RH6,0,0,Bev%F6lkerung_nach_Altersgruppen_und_Geschlecht.html. Assessed 8 June 2014

21.

Bosch JL, Weiss JP (2013) The prevalence and causes of nocturia. J Urol 189:S86–S92PubMedCrossRef

22.

Clark JA, Inui TS, Silliman RA, Bokhour BG, Krasnow SH, Robinson RA et al (2003) Patients’ perceptions of quality of life after treatment for early prostate cancer. J Clin Oncol 21:3777–3784PubMedCrossRef

23.

Homma Y, Yamaguchi T, Kondo Y, Horie S, Takahashi S, Kitamura T (2002) Significance of nocturia in the International prostate symptom score for benign prostatic hyperplasia. J Urol 167:172–176PubMedCrossRef

24.

Chen FY, Dai YT, Liu CK, Yu HJ, Liu CY, Chen TH (2007) Perception of nocturia and medical consulting behavior among community-dwelling women. Int Urogynecol J 18:431–436CrossRef

Title: Nocturia and its impact on health-related quality of life and health care seeking behaviour in German community-dwelling men aged 50 years or older
Authors: Matthias Oelke
Birgitt Wiese
Richard Berges
Publication date: 01-10-2014
Publisher: Springer Berlin Heidelberg
Published in: World Journal of Urology / Issue 5/2014
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-014-1374-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Nocturia and its impact on health-related quality of life and health care seeking behaviour in German community-dwelling men aged 50 years or older

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

Please log in to get access to this content

Other articles of this Issue 5/2014

Perforation during TUR of bladder tumours influences the natural history of superficial bladder cancer

Is there a volume–outcome relationship for partial nephrectomy?

Nocturia: state of the art and critical analysis of current assessment and treatment strategies

Redo-urethroplasty: comparison of early functional results and quality of life in penile and bulbar strictures

Is there an anti-androgen withdrawal syndrome for enzalutamide?

Effects of tadalafil on nighttime voiding (nocturia) in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: a post hoc analysis of pooled data from four randomized, placebo-controlled clinical studies