Skip to main content
Top
Published in: Intensive Care Medicine 11/2016

01-11-2016 | Editorial

No harm, no benefit: should we give up with neurally adjusted ventilatory assist?

Authors: Paolo Navalesi, Federico Longhini

Published in: Intensive Care Medicine | Issue 11/2016

Login to get access

Excerpt

Mechanical ventilation is a frequent reason for admitting a patient to the intensive care unit (ICU) and is therefore one of the most common forms of treatment we use in our ICU daily practice. We apply it for varying reasons, the most frequent being an episode of acute respiratory failure (ARF) that may be caused by a variety of conditions [1]. …
Literature
1.
go back to reference Esteban A, Frutos-Vivar F, Muriel A, Ferguson ND, Penuelas O, Abraira V, Raymondos K, Rios F, Nin N, Apezteguia C, Violi DA, Thille AW, Brochard L, Gonzalez M, Villagomez AJ, Hurtado J, Davies AR, Du B, Maggiore SM, Pelosi P, Soto L, Tomicic V, D’Empaire G, Matamis D, Abroug F, Moreno RP, Soares MA, Arabi Y, Sandi F, Jibaja M, Amin P, Koh Y, Kuiper MA, Bulow HH, Zeggwagh AA, Anzueto A (2013) Evolution of mortality over time in patients receiving mechanical ventilation. Am J Respir Crit Care Med 188:220–230CrossRefPubMed Esteban A, Frutos-Vivar F, Muriel A, Ferguson ND, Penuelas O, Abraira V, Raymondos K, Rios F, Nin N, Apezteguia C, Violi DA, Thille AW, Brochard L, Gonzalez M, Villagomez AJ, Hurtado J, Davies AR, Du B, Maggiore SM, Pelosi P, Soto L, Tomicic V, D’Empaire G, Matamis D, Abroug F, Moreno RP, Soares MA, Arabi Y, Sandi F, Jibaja M, Amin P, Koh Y, Kuiper MA, Bulow HH, Zeggwagh AA, Anzueto A (2013) Evolution of mortality over time in patients receiving mechanical ventilation. Am J Respir Crit Care Med 188:220–230CrossRefPubMed
2.
go back to reference Rittayamai N, Katsios CM, Beloncle F, Friedrich JO, Mancebo J, Brochard L (2015) Pressure-controlled vs volume-controlled ventilation in acute respiratory failure: a physiology-based narrative and systematic review. Chest 148:340–355CrossRefPubMed Rittayamai N, Katsios CM, Beloncle F, Friedrich JO, Mancebo J, Brochard L (2015) Pressure-controlled vs volume-controlled ventilation in acute respiratory failure: a physiology-based narrative and systematic review. Chest 148:340–355CrossRefPubMed
3.
go back to reference Chao DC, Scheinhorn DJ, Stearn-Hassenpflug M (1997) Patient-ventilator trigger asynchrony in prolonged mechanical ventilation. Chest 112:1592–1599CrossRefPubMed Chao DC, Scheinhorn DJ, Stearn-Hassenpflug M (1997) Patient-ventilator trigger asynchrony in prolonged mechanical ventilation. Chest 112:1592–1599CrossRefPubMed
4.
go back to reference Thille AW, Rodriguez P, Cabello B, Lellouche F, Brochard L (2006) Patient–ventilator asynchrony during assisted mechanical ventilation. Intensive Care Med 32:1515–1522CrossRefPubMed Thille AW, Rodriguez P, Cabello B, Lellouche F, Brochard L (2006) Patient–ventilator asynchrony during assisted mechanical ventilation. Intensive Care Med 32:1515–1522CrossRefPubMed
5.
go back to reference de Wit M, Miller KB, Green DA, Ostman HE, Gennings C, Epstein SK (2009) Ineffective triggering predicts increased duration of mechanical ventilation. Crit Care Med 37:2740–2745CrossRefPubMed de Wit M, Miller KB, Green DA, Ostman HE, Gennings C, Epstein SK (2009) Ineffective triggering predicts increased duration of mechanical ventilation. Crit Care Med 37:2740–2745CrossRefPubMed
6.
go back to reference Navalesi P, Costa R (2003) New modes of mechanical ventilation: proportional assist ventilation, neurally adjusted ventilatory assist, and fractal ventilation. Curr Opin Crit Care 9:51–58CrossRefPubMed Navalesi P, Costa R (2003) New modes of mechanical ventilation: proportional assist ventilation, neurally adjusted ventilatory assist, and fractal ventilation. Curr Opin Crit Care 9:51–58CrossRefPubMed
7.
8.
go back to reference Demoule A, Clavel M, Rolland-Debord C, Perbet S, Terzi N, Kouatchet A, Wallet F, Roze H, Vargas F, Guerin C, Dellamonica J, Jaber S, Brochard L, Similowski T (2016) Neurally adjusted ventilatory assist as an alternative to pressure support ventilation in adults: a French multicentre randomized trial. Intensive Care Med. doi:10.1007/s00134-016-4447-8 Demoule A, Clavel M, Rolland-Debord C, Perbet S, Terzi N, Kouatchet A, Wallet F, Roze H, Vargas F, Guerin C, Dellamonica J, Jaber S, Brochard L, Similowski T (2016) Neurally adjusted ventilatory assist as an alternative to pressure support ventilation in adults: a French multicentre randomized trial. Intensive Care Med. doi:10.​1007/​s00134-016-4447-8
9.
go back to reference Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, Slutsky AS, Meade MO (2013) High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med 368:795–805CrossRefPubMed Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, Slutsky AS, Meade MO (2013) High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med 368:795–805CrossRefPubMed
10.
go back to reference Thille AW, Cabello B, Galia F, Lyazidi A, Brochard L (2008) Reduction of patient–ventilator asynchrony by reducing tidal volume during pressure-support ventilation. Intensive Care Med 34:1477–1486CrossRefPubMed Thille AW, Cabello B, Galia F, Lyazidi A, Brochard L (2008) Reduction of patient–ventilator asynchrony by reducing tidal volume during pressure-support ventilation. Intensive Care Med 34:1477–1486CrossRefPubMed
Metadata
Title
No harm, no benefit: should we give up with neurally adjusted ventilatory assist?
Authors
Paolo Navalesi
Federico Longhini
Publication date
01-11-2016
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 11/2016
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-016-4484-3

Other articles of this Issue 11/2016

Intensive Care Medicine 11/2016 Go to the issue

Understanding the Disease

Understanding PK/PD