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Acta Neurochirurgica

Published in:

01-04-2018 | Original Article - Neurosurgery Training

No correlation between radiological and clinical outcome 1 year following cervical arthrodesis

Authors: Ehab Shiban, Moritz Nies, Johann Kogler, Lorenz Kogler, Pedro Ribeiro da Cunha, Bernhard Meyer, Jens Lehmberg

Published in: Acta Neurochirurgica | Issue 4/2018

Abstract

Aim

To correlate clinical and radiological outcome following one- and two-level anterior cervical discectomy and fusion (ACDF) with stand-alone polyetheretherketone (PEEK) cages filled with demineralized bone matrix (DBM).

Methods

We performed a retrospective review of a consecutive patient cohort with degenerative disc disease that underwent ACDF with stand-alone PEEK cages filled with demineralized bone matrix (DBM) between 2010 and 2013 with a minimum follow-up of 12 months. Changes in the operated segments were measured and compared to radiographs directly after surgery. Clinical outcome was evaluated by a physical examination, pain by visual analog scale (VAS) for arm and neck. Health-related quality of life was measured using the EuroQOL questionnaire (EQ-5D).

Results

Of 282 consecutive cases, follow-up data were obtained from 194 (69%) cases. The median age at presentation was 54 years and 91 patients were male (46%). Ninety-eight and 96 patients had one- and two-level surgeries, respectively. Mean VAS pain was reduced from 5.2 ± 3.6 to 2.6 ± 2.4 (p < 0.001) and from 5.8 ± 3.3 to 2.1 ± 2.7 (p < 0.001) in the myelopathy and radiculopathy group, respectively. Fusion was achieved in 79 and 82% of segments in one- and two-level surgeries, respectively. Cervical alignment was better in 10 and 1%, similar in 68 and 76%, worse in 23 and 23% in one- and two-level surgeries, respectively. Subsidence was observed in 44 and 34% of segments in one- and two-level surgeries, respectively. Follow-up operations due to symptomatic adjacent disc disease or implant failure were needed in 13 (7%) and 15 (8%) of cases, respectively. Subsidence, adjacent disc disease, and cervical alignment all had no influence on the clinical outcome.

Conclusions

The clinical outcome after ACDF with PEEK cages filled with demineralized bone matrix is highly satisfactory. Radiological signs of non-fusion, subsidence, and cervical alignment have no influence on clinical outcome.

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Title: No correlation between radiological and clinical outcome 1 year following cervical arthrodesis
Authors: Ehab Shiban
Moritz Nies
Johann Kogler
Lorenz Kogler
Pedro Ribeiro da Cunha
Bernhard Meyer
Jens Lehmberg
Publication date: 01-04-2018
Publisher: Springer Vienna
Published in: Acta Neurochirurgica / Issue 4/2018
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI: https://doi.org/10.1007/s00701-018-3495-y

At a glance: The STEP trials

Springer Medicine

No correlation between radiological and clinical outcome 1 year following cervical arthrodesis

Abstract

Aim

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Aim

Methods

Results

Conclusions

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