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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-02-2019 | Retinal Disorders

New clinical ultrahigh-resolution SD-OCT using A-scan matching algorithm

Authors: Yoshitsugu Matsui, Mineo Kondo, Eriko Uchiyama, Ryohei Mityata, Hisashi Matsubara

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 2/2019

Abstract

Purpose

A new clinical ultrahigh-resolution spectral domain optical coherence tomography (UHR-SD-OCT) system using an original averaging technique named “A-scan matching algorithm” was developed. The aim of this study was to determine whether our new UHR-SD-OCT system can obtain clearer sectional images of the retina than conventional standard resolution SD-OCT systems (SR-SD-OCT).

Methods

We recorded horizontal B-scan images of 42 normal eyes using our new UHR-SD-OCT device (Bi-μ, Kowa) and a conventional SR-SD-OCT (Spectralis, Heidelberg). To evaluate the clarity of the interdigitation zone (IZ) subjectively, the integrity of IZ was divided into three types by two raters. To evaluate the clarity of the IZ objectively, a peak height score (PHS) was calculated at five different points of the macula using the longitudinal reflectivity profile.

Results

The mean (± SD) of the subjective visibility score of the IZ in the UHR-SD-OCT images was 2.64 ± 0.54 which was significantly higher than the 2.46 ± 0.46 in the SR-SD-OCT images (P = 0.02). The PHS was also significantly higher for the UHR-SD-OCT than for the SR-SD-OCT images at all five locations (all P < 0.01).

Conclusion

The results indicate that the newly developed clinical UHR-SD-OCT instrument using the A-scan matching algorithm can obtain clearer images of the IZ, and they suggest that this device should be clinically useful in detecting finer structural abnormalities of the outer retina.

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Title: New clinical ultrahigh-resolution SD-OCT using A-scan matching algorithm
Authors: Yoshitsugu Matsui
Mineo Kondo
Eriko Uchiyama
Ryohei Mityata
Hisashi Matsubara
Publication date: 01-02-2019
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 2/2019
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-018-4183-6

At a glance: The STEP trials

Springer Medicine

New clinical ultrahigh-resolution SD-OCT using A-scan matching algorithm

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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