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Journal of Neuroinflammation
Published in: Journal of Neuroinflammation 1/2018

Open Access 01-12-2018 | Review

Neutrophils in traumatic brain injury (TBI): friend or foe?

Authors: Yang-Wuyue Liu, Song Li, Shuang-Shuang Dai

Published in: Journal of Neuroinflammation | Issue 1/2018

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Abstract

Our knowledge of the pathophysiology about traumatic brain injury (TBI) is still limited. Neutrophils, as the most abundant leukocytes in circulation and the first-line transmigrated immune cells at the sites of injury, are highly involved in the initiation, development, and recovery of TBI. Nonetheless, our understanding about neutrophils in TBI is obsolete, and mounting evidences from recent studies have challenged the conventional views. This review summarizes what is known about the relationships between neutrophils and pathophysiology of TBI. In addition, discussions are made on the complex roles as well as the controversial views of neutrophils in TBI.
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Metadata
Title
Neutrophils in traumatic brain injury (TBI): friend or foe?
Authors
Yang-Wuyue Liu
Song Li
Shuang-Shuang Dai
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Journal of Neuroinflammation / Issue 1/2018
Electronic ISSN: 1742-2094
DOI
https://doi.org/10.1186/s12974-018-1173-x

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