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Neurotherapeutics

Issue 1/2007

New Antiepileptic Drugs: Discovery, Development, and Update

Content (23 Articles)

Editorial

New antiepileptic drugs—Discovery, development, and update

Roger J. Porter, Jacqueline A. French

Discovery of antiepileptic drugs

Misty Smith, Karen S. Wilcox, H. Steve White

Molecular targets for antiepileptic drug development

Brian S. Meldrum, Michael A. Rogawski

Brivaracetam (UCB 34714)

Philipp von Rosenstiel

Eslicarbazepine acetate (BIA 2-093)

Luis Almeida, Patrício Soares-da-Silva

Fluorofelbamate

Bryan A. Roecklein, Harry J. Sacks, Henry Mortko, James Stables

Ganaxolone

Virinder Nohria, Earl Giller

Carisbamate (RWJ-333369)

Gerald P. Novak, Michael Kelley, Peter Zannikos, Brian Klein

Safinamide

Ruggero G. Fariello

Seletracetam (UCB 44212)

Barbara Bennett, Alain Matagne, Philippe Michel, Michèle Leonard, Miranda Cornet, Marie-Anne Meeus, Nathalie Toublanc

Stiripentol

Catherine Chiron

Talampanel

John F. Howes, Cynthia Bell

Valproic acid: Second generation

Meir Bialer, Boris Yagen

Clobazam

Yu-tze Ng, Stephen D. Collins

Lacosamide

Pamela Doty, G. David Rudd, Thomas Stoehr, Dirk Thomas

Retigabine

Roger J. Porter, Virinder Nohria, Chris Rundfeldt

Rufinamide

Santiago Arroyo

Vigabatrin

James W. Wheless, R. Eugene Ramsay, Stephen D. Collins