Published in:
01-02-2017 | Neurology of Systemic Diseases (J Biller, Section Editor)
Neurological Complications of the Leukemias Across the Ages
Authors:
Stephanie Berg, Sucha Nand
Published in:
Current Neurology and Neuroscience Reports
|
Issue 2/2017
Login to get access
Abstract
Purpose of Review
Acute and chronic leukemias are heterogeneous diseases and can affect any part of the body upon initial discovery. Understanding the sequela of systemic involvement is key for proper diagnosis and treatment.
Recent Findings
Over the decades, new research has emerged regarding neurological complications of the myeloid or lymphoid leukemias. Central nervous system involvement usually confers a poor prognosis and requires emergent treatment. Standard of care still involves systemic therapy, intrathecal administration of chemotherapeutic agents, and cranial radiation. Treatment-related side effects can occur and need to be recognized by any practitioner involved with patient care.
Summary
It is imperative to understand neurologic complications from leukemia to prevent delays and initiate necessary treatment to maintain neurologic and cognitive function.