Published in:
01-12-2017 | Preclinical and Psychophysiology (F Guarraci and L Marson, Section Editors)
Neural and Endocrine Factors Contribute to the Comorbidity of Urinary and Sexual Dysfunctions
Authors:
Yolanda Cruz, R. A. Lucio, J. L. Palacios
Published in:
Current Sexual Health Reports
|
Issue 4/2017
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Abstract
Purpose of Review
The purpose of this study is to determine whether neural and/or endocrine factors are related to urinary and sexual disease comorbidity.
Recent Findings
Common neural circuitries at cerebral, spinal, and peripheral levels participate in the control of urogenital organs. The convergence and crosstalk of pelvic organ information in the central nervous system may underlie comorbidity of urinary-sexual dysfunctions, and also subserve the success of genital and tibial nerve stimulation therapies to treat overactive bladder. Nonetheless, the relevance of gonadal hormones to the pathophysiology of urinary-sexual functions is still controversial.
Summary
The etiology of urinary dysfunctions is usually considered to be at the periphery. However, spinal and supraspinal sites controlling urogenital organs deteriorate with age and can be another factor for urogenital dysfunctions. In addition, although it is well recognized that urinary incontinence has a negative impact on sexual functions, there is no research investigating the impact of sexual function/dysfunction on the urinary organs.