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Pediatric Nephrology
Published in: Pediatric Nephrology 9/2009

01-09-2009 | Brief Report

Nephrogenic diabetes insipidus: treat with caution

Authors: Thierry Boussemart, Jacqueline Nsota, Dominique Martin–Coignard, Gérard Champion

Published in: Pediatric Nephrology | Issue 9/2009

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Abstract

Current therapy for congenital nephrogenic diabetes insipidus consists of appropriate water intake coupled with decreased urine output obtained by means of a low-sodium diet and a combination of thiazide diuretics with renal prostaglandins inhibitors or amiloride. We report a case of congenital nephrogenic diabetes insipidus that was complicated by paradoxical water intoxication secondary to liberal water intake and the initiation of hydrochlorothiazide and indomethacin combination therapy. This report emphasizes the importance of evaluating the water balance and of a quick response with strict protocols following the initiation of indomethacin and thiazide diuretics in nephrogenic diabetes insipidus.
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Metadata
Title
Nephrogenic diabetes insipidus: treat with caution
Authors
Thierry Boussemart
Jacqueline Nsota
Dominique Martin–Coignard
Gérard Champion
Publication date
01-09-2009
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Nephrology / Issue 9/2009
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-009-1187-9

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