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Published in: African Journal of Urology 1/2021

Open Access 01-12-2021 | Nephrectomy | Original Research

Evaluating the differences in the early laparoscopic donor nephrectomy learning curves of a Swiss high volume transplant program and a South African low volume transplant program after knowledge transfer

Authors: André van der Merwe, N. Nicole Ebinger Mundorf, H. van Heerden, G. Bonkat, H. van Deventer, G. Mantica, Z. Keyser, A. Bachmann

Published in: African Journal of Urology | Issue 1/2021

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Abstract

Background

To describe the retroperitoneoscopic donor nephrectomy learning curve differences between a high volume (training) hospital in Basel, Switzerland, and a low volume (trainee) hospital in Cape Town, South Africa, after knowledge transfer. The South African hospital is resource constraint in hospital and training equipment. Techniques for performing the surgery were near identical.

Methods

Both units maintained prospective databases. Comparisons were made of the first 74 cases in each database: Basel’s series were from 19 January 2001 until 28 June 2004, while the Cape Town Hospital were from 8 April 2008 until 15 July 2008. Four surgeons operated in the Basel group, while only one surgeon operated in the Cape Town group. Variables compared include operating time (first skin incision until kidney was extracted), warm ischaemic time (renal arterial occlusion until cold bench reperfusion), blood loss, graft function, and hospital stay. We also analysed the first and last 25 cases of each series. Subgroup analysis of a single Basel surgeon was conducted.

Results

Donor age (means: Basel vs. Cape Town 54 vs. 33 p < 0.0001) and gender (males vs. females Cape Town 57% male and Basel 31% male) differed widely. The Basel group did more left-sided operations (72% vs. 58%). Operative times, blood loss and donor creatinine did not differ. Warm ischaemic time was significantly shorter in the Basel group (Cape Town mean 204 s Basel mean 130 s P = 0.0023). There was double the number of early graft failures in the South African group (six vs. three)—not related to donor surgery. Both groups showed a decline in operating times, plateauing at 30–34 cases.

Conclusions

There are statistically significant differences in some aspects of the learning curves of the Swiss (training) and South African (trainee) hospitals. These differences are clinically not pronounced, and the knowledge transfer was worth the effort.
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Metadata
Title
Evaluating the differences in the early laparoscopic donor nephrectomy learning curves of a Swiss high volume transplant program and a South African low volume transplant program after knowledge transfer
Authors
André van der Merwe
N. Nicole Ebinger Mundorf
H. van Heerden
G. Bonkat
H. van Deventer
G. Mantica
Z. Keyser
A. Bachmann
Publication date
01-12-2021
Publisher
Springer Berlin Heidelberg
Published in
African Journal of Urology / Issue 1/2021
Print ISSN: 1110-5704
Electronic ISSN: 1961-9987
DOI
https://doi.org/10.1186/s12301-021-00215-0

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