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BMC Pediatrics

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Open Access 01-12-2021 | Neonatal Sepsis | Research

Determination of neonatal case-specific fatality rates in a tertiary health institution in North Central Nigeria

Authors: L. I. Audu, A. T. Otuneye, A. B. Mairami, M. Mukhtar-Yola, L. J. Mshelia

Published in: BMC Pediatrics | Issue 1/2021

Abstract

Background

The current neonatal mortality rate in Nigeria (37/1000) is among the highest in the world and the major causes have consistently been reported as sepsis, perinatal asphyxia and prematurity. However, case-specific fatality which defines the risk of dying from these and other neonatal morbidities is rarely emphasized. Determination of case-specific fatality rates (CSFR) may inform a change in our current approach to neonatal care interventions which may eventually bring about the much-needed reduction in our neonatal mortality rate. Our aim was to determine the case-specific fatality rates for the common causes of mortality among hospitalized neonates at the National Hospital Abuja (NHA).

Methods

Relevant demographic and clinical data on all neonates admitted into the NICU at the NHA over a period of 13 months (January 2017 to February 2018) were extracted from the Neonatal Registry database and analyzed using appropriate statistical methods with the SPSS version 20 software. The case-specific fatality rates were computed for the predominant morbidities in addition to determination of the neonatal mortality rates and associated risk factors.

Results and conclusion

A total of 730 neonates were admitted, out of which 391 (53.6%) were females, 396 (54.5%) were inborn and 396 (54.2%) were term. The three most prevalent morbidities were prematurity 272(37.2%), neonatal Jaundice 208(28.4%) and perinatal asphyxia 91(12.5%) while the most common causes of mortality were prematurity 47/113(41.6%), congenital malformations 27/113(23.9%) and perinatal asphyxia 26/113(23%). Congenital malformations had the highest case-specific fatality 27/83(32.5%) followed by Perinatal Asphyxia 26/91(28.6%) and prematurity 47/272(20.7%). The mortality pattern differed between inborn and out born babies. Implications of these case-specific fatality rates for targeted interventions are discussed.

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Title: Determination of neonatal case-specific fatality rates in a tertiary health institution in North Central Nigeria
Authors: L. I. Audu
A. T. Otuneye
A. B. Mairami
M. Mukhtar-Yola
L. J. Mshelia
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Neonatal Sepsis
Perinatal Asphyxia
Published in: BMC Pediatrics / Issue 1/2021
Electronic ISSN: 1471-2431
DOI: https://doi.org/10.1186/s12887-021-02778-x

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Springer Medicine

Determination of neonatal case-specific fatality rates in a tertiary health institution in North Central Nigeria

Abstract

Background

Methods

Results and conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results and conclusion

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