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01-01-2016 | Original Scientific Report

Negative Fine-Needle Aspiration in Patients with Goiter: Should We Doubt It?

Authors: Michal Mekel, Hayim Gilshtein, Abbas Al-Kurd, Bishara Bishara, Michael M. Krausz, Herbert R. Freund, Yoram Kluger, Ahmed Eid, Haggi Mazeh

Published in: World Journal of Surgery | Issue 1/2016

Abstract

Background

Epidemiologic studies demonstrated higher incidence of thyroid cancer in patients with multinodular goiters compared to the general population. The aim of this study was to evaluate the risk of finding significant thyroid cancer in patients undergoing thyroidectomy for presumed benign disease.

Methods

The records of 273 patients operated for indications other than cancer or indeterminate cytology were reviewed and analyzed.

Results

202 (74 %) patients had a preoperative fine-needle aspiration (FNA) performed. FNA was benign in 96 % of patients and non-diagnostic in 4 %. Malignancy was unexpectedly found in 50 (19 %) patients. Papillary carcinoma constituted 94 % of cancers and 86 % of cancers were incidental microcarcinomas. Only 7 (2.6 %) patients of the entire cohort had tumors greater than 1 cm, of those only 3 had a previous benign FNA (false-negative rate 1.5 %).

Conclusions

The rate of significant thyroid cancer found unexpectedly in resected goiters is extremely low. A negative FNA excludes significant cancer with near certainty.

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Title: Negative Fine-Needle Aspiration in Patients with Goiter: Should We Doubt It?
Authors: Michal Mekel
Hayim Gilshtein
Abbas Al-Kurd
Bishara Bishara
Michael M. Krausz
Herbert R. Freund
Yoram Kluger
Ahmed Eid
Haggi Mazeh
Publication date: 01-01-2016
Publisher: Springer International Publishing
Published in: World Journal of Surgery / Issue 1/2016
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-015-3216-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Negative Fine-Needle Aspiration in Patients with Goiter: Should We Doubt It?

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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