Published in:
01-09-2012
Necrotizing Infundibuloneurohypophysitis: Case Report and Literature Review
Authors:
Anick Nater, Luis V. Syro, Fabio Rotondo, Bernd W. Scheithauer, Veronica Abad, Carolina Jaramillo, Kalman Kovacs, Eva Horvath, Michael Cusimano
Published in:
Endocrine Pathology
|
Issue 3/2012
Login to get access
Excerpt
Several conditions may lead to pituitary necrosis: Sheehan syndrome, increased intracranial pressure, traumatic pituitary injury, thrombosis of the vessels perfusing the pituitary, ischemia, as well as various infections and autoimmune processes. Necrosis may develop in the anterior and posterior lobes, as well as in the pituitary stalk and infundibulum. Hypophysitis is a chronic inflammatory disorder resulting from an autoimmune process (primary hypophysitis) [
1,
2] or from an identified agent, such as infection (secondary hypophysitis) [
3]. By histology, in various forms of hypophysitis, necrotic areas may be apparent. …