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Published in: Current Sleep Medicine Reports 2/2023

Open Access 01-06-2023 | Narcolepsy

The evolving diagnosis and classification of CNS hypersomnolence disorders

Authors: Gert Jan Lammers, Ulf Kallweit

Published in: Current Sleep Medicine Reports | Issue 2/2023

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Abstract

Purpose of Review

We describe the evolution and limitations of current diagnostic criteria and classification systems of CNS hypersomnolence disorders and propose some changes.

Recent Findings

An unsupervised cluster analysis of 1100 Europeans with hypersomnolence identified the narcolepsy type 1 phenotype but not other categories listed in ICSD-3.

Summary

There are long-standing unsolved issues regarding the diagnosis and classification of central disorders of hypersomnolence. These include delineating and identifying phenotypes and unique conditions (“sui generis”), sleep deprivation’s impact on phenotypes and how to separate sleep deprivation as a trigger from other causes, as well as the association of excessive sleepiness with other disorders. We discuss these issues and present a novel, straightforward classification system with consistent terminology to get out of the impasse and do justice to people with hypersomnolence.
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Metadata
Title
The evolving diagnosis and classification of CNS hypersomnolence disorders
Authors
Gert Jan Lammers
Ulf Kallweit
Publication date
01-06-2023
Publisher
Springer International Publishing
Published in
Current Sleep Medicine Reports / Issue 2/2023
Electronic ISSN: 2198-6401
DOI
https://doi.org/10.1007/s40675-023-00250-z

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