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01-12-2020 | Naloxone | Letter

Naloxone should remain the appropriate antidote to treat opioid overdose

Authors: Bruno Mégarbane, Lucie Chevillard, Dominique Vodovar

Published in: Critical Care | Issue 1/2020

Excerpt

To the Editor, …

Zamani N, Buckley NA, Hassanian-Moghaddam H. Buprenorphine to reverse respiratory depression from methadone overdose in opioid-dependent patients: a prospective randomized trial. Crit Care. 2020;24:44. https://doi.org/10.1186/s13054-020-2740-y.

Boyer EW. Management of opioid analgesic overdose. N Engl J Med. 2012;367:146–55.CrossRef

Mégarbane B, Buisine A, Jacobs F, Résière D, Chevillard L, Vicaut E, Baud FJ. Prospective comparative assessment of buprenorphine overdose with heroin and methadone: clinical characteristics and response to antidotal treatment. J Subst Abus Treat. 2010;38:403–7.CrossRef

Cohier C, Chevillard L, Salle S, Risède P, Roussel O, Mégarbane B. Editor’s highlight: neurorespiratory effects of buprenorphine and ethanol in combination: a mechanistic study of drug-drug interactions in the rat. Toxicol Sci. 2017;155:389–99.CrossRef

Cohier C, Chevillard L, Risède P, Roussel O, Mégarbane B. Respiratory effects of buprenorphine/naloxone alone and in combination with diazepam in naive and tolerant rats. Toxicol Lett. 2014;228:75–84.CrossRef

Chenaf C, Kaboré JL, Delorme J, et al. Prescription opioid analgesic use in France: trends and impact on morbidity-mortality. Eur J Pain. 2019;23(1):124–34. https://doi.org/10.1002/ejp.1291.CrossRefPubMed

Akhgari M, Amini-Shirazi N, Iravani FS. Forensic toxicology perspectives of methadone-associated deaths in Tehran, Iran, a 7-year overview. Basic Clin Pharmacol Toxicol. 2018;122(4):436–41.CrossRef

Farkas A, et al. Pulmonary complications of opioid overdose treated with naloxone. Ann Emerg Med. 2020;75(1):39–48.CrossRef

Fox L, Nelson LS. Emergency department initiation of buprenorphine for opioid use disorder: current status, and future potential. CNS Drugs. 2019;33(12):1147–54.CrossRef

Title: Naloxone should remain the appropriate antidote to treat opioid overdose
Authors: Bruno Mégarbane
Lucie Chevillard
Dominique Vodovar
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Naloxone
Buprenorphine
Opioids
Opioids
Methadone
Published in: Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/s13054-020-2835-5

At a glance: The STEP trials

Springer Medicine

Naloxone should remain the appropriate antidote to treat opioid overdose

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At a glance: The STEP trials

Springer Medicine

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