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01-10-2008 | Commentary

Myocardial protection in sepsis

Authors: Simon Shakar, Brian D Lowes

Published in: Critical Care | Issue 5/2008

Abstract

Sepsis with myocardial dysfunction is seen commonly. Beta-blockers have been used successfully to treat chronic heart failure based on the premise that chronically elevated adrenergic drive is detrimental to the myocardium. However, recent reports on the acute use of beta-blockers in situations with potential hemodynamic compromise have shown the risks associated with this approach. In critical situations, the main effect of adrenergic activation is to support cardiovascular function. Caution should be exercised in designing studies to assess beta-blockers in septic patients.

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Title: Myocardial protection in sepsis
Authors: Simon Shakar
Brian D Lowes
Publication date: 01-10-2008
Publisher: BioMed Central
Published in: Critical Care / Issue 5/2008
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc6978

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Myocardial protection in sepsis

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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