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The International Journal of Cardiovascular Imaging

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01-06-2019 | Myocardial Infarction | Original Paper

The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT

Authors: Veronika Bednárová, Vladimír Kincl, Milan Kamínek, Jiří Vašina, Roman Panovský, Jan Máchal

Published in: The International Journal of Cardiovascular Imaging | Issue 6/2019

Abstract

The purpose of this study was to assess the prognostic value of ultra-low dose thallium myocardial perfusion imaging. Three hundred and sixty-six patients (245 men) underwent ultra-low dose stress-redistribution imaging on CZT SPECT camera GE Discovery NM 530c. The stress test was performed by bicycle ergometry or regadenoson injection. The activity of 0.5 MBq (0.014 mCi) Tl-201 chloride per kilogram of body weight was administered. The stress images were acquired immediately and redistribution images were taken after 3 h. Patient follow-up was focused on combined end-point (death, myocardial infarction, unstable angina, revascularization and hospitalization for heart failure). Data analysis was performed from hospital database, with a mean period 23 months. Patients with revascularization within 1 month after SPECT was excluded as revascularization for diagnosis. Ischaemia on SPECT was found in 72 patients, 294 patients were without ischaemia. In patients with ischaemia there were 21 (29.2%) subjects with cardiac events, and 23 (7.9%) in patients without ischaemia (HR 4.15, 95% CI 2.30–7.51, p < 0.0001). Ultra-low dose thallium perfusion imaging using CZT camera provides very good prognostic results in assessment of myocardial ischaemia.

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Title: The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT
Authors: Veronika Bednárová
Vladimír Kincl
Milan Kamínek
Jiří Vašina
Roman Panovský
Jan Máchal
Publication date: 01-06-2019
Publisher: Springer Netherlands
Keywords: Myocardial Infarction
Unstable Angina
Published in: The International Journal of Cardiovascular Imaging / Issue 6/2019
Print ISSN: 1569-5794
Electronic ISSN: 1875-8312
DOI: https://doi.org/10.1007/s10554-019-01535-7

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The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT

Abstract

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