Skip to main content
Top
Published in: BMC Health Services Research 1/2024

Open Access 01-12-2024 | Myocardial Infarction | Research

Impact of early death recording on international comparison of acute myocardial infarction mortality – administrative hospital data study using the example of Germany and the United States

Authors: Ulrike Nimptsch, Thomas Mansky, Reinhard Busse

Published in: BMC Health Services Research | Issue 1/2024

Login to get access

Abstract

Background

In-hospital mortality from acute myocardial infarction (AMI) is widely used in international comparisons as an indicator of health system performance. Because of the high risk of early death after AMI, international comparisons may be biased by differences in the recording of early death cases in hospital inpatient data. This study examined whether differences in the recording of early deaths affect international comparisons of AMI in-hospital mortality by using the example of Germany and the United States, and explored approaches to address this issue.

Methods

The German Diagnosis-Related Groups Statistics (DRG Statistics), the U.S. National Inpatient Sample (NIS) and the U.S. Nationwide Emergency Department Sample (NEDS) were analysed from 2014 to 2019. Cases with treatment for AMI were identified in German and U.S. inpatient data. AMI deaths occurring in the emergency department (ED) without inpatient admission were extracted from NEDS data. 30-day in-hospital mortality figures were calculated according to the OECD indicator definition (unlinked data) and modified by including ED deaths, or excluding all same-day cases.

Results

German age-and-sex standardized 30-day in-hospital mortality was substantially higher compared to the U.S. (in 2019, 7.3% vs. 4.6%). The ratio of German vs. U.S. mortality was 1.6. After inclusion of ED deaths in U.S. data this ratio declined to 1.4. Exclusion of same-day cases in German and U.S. data led to a similar ratio.

Conclusions

While short-duration treatments due to early death are generally recorded in German inpatient data, in U.S. inpatient data those cases are partially missing. Excluding cases with short-duration treatment from the calculation of mortality indicators could be a feasible approach to account for differences in the recording of early deaths, that might be existent in other countries as well.
Appendix
Available only for authorised users
Literature
1.
go back to reference Ibanez B, James S, Agewall S, et al. 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2018;39(2):119–77.CrossRefPubMed Ibanez B, James S, Agewall S, et al. 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2018;39(2):119–77.CrossRefPubMed
2.
go back to reference Kelley E. Health, spending and the effort to improve quality in OECD countries: a review of the data. J R Soc Promot Health. 2007;127(2):64–71.CrossRefPubMed Kelley E. Health, spending and the effort to improve quality in OECD countries: a review of the data. J R Soc Promot Health. 2007;127(2):64–71.CrossRefPubMed
5.
go back to reference Bolczek C, Nimptsch U, Möckel M, Mansky T. Health care provision and volume-outcome relationship for acute myocardial infarction: long-term analysis of german nationwide hospital discharge data 2005–2015. Gesundheitswesen. 2020;82(10):777–85. Bolczek C, Nimptsch U, Möckel M, Mansky T. Health care provision and volume-outcome relationship for acute myocardial infarction: long-term analysis of german nationwide hospital discharge data 2005–2015. Gesundheitswesen. 2020;82(10):777–85.
7.
go back to reference Nimptsch U, Mansky T. G-IQI | German Inpatient Indicators Version 5.3. Bundesreferenzwerte für das Auswertungsjahr 2019. Working Papers in Health Services Research Vol 4. Berlin: Universitätsverlag der Technischen Universität Berlin; 2021. https://doi.org/10.14279/depositonce-12342 Nimptsch U, Mansky T. G-IQI | German Inpatient Indicators Version 5.3. Bundesreferenzwerte für das Auswertungsjahr 2019. Working Papers in Health Services Research Vol 4. Berlin: Universitätsverlag der Technischen Universität Berlin; 2021. https://​doi.​org/​10.​14279/​depositonce-12342
8.
go back to reference Kuch B, Bolte HD, Hoermann A, Meisinger C, Loewel H. What is the real hospital mortality from acute myocardial infarction? Epidemiological vs clinical view. Eur Heart J. 2002;23(9):714–20.CrossRefPubMed Kuch B, Bolte HD, Hoermann A, Meisinger C, Loewel H. What is the real hospital mortality from acute myocardial infarction? Epidemiological vs clinical view. Eur Heart J. 2002;23(9):714–20.CrossRefPubMed
9.
go back to reference Vallabhajosyula S, Dunlay SM, Bell MR, Miller PE, Cheungpasitporn W, Sundaragiri PR, Kashani K, Gersh BJ, Jaffe AS, Holmes DR, Barsness GW. Epidemiological trends in the timing of in-hospital death in acute myocardial infarction – cardiogenic shock in the United States. J Clin Med. 2020;9(7):2094.CrossRefPubMedPubMedCentral Vallabhajosyula S, Dunlay SM, Bell MR, Miller PE, Cheungpasitporn W, Sundaragiri PR, Kashani K, Gersh BJ, Jaffe AS, Holmes DR, Barsness GW. Epidemiological trends in the timing of in-hospital death in acute myocardial infarction – cardiogenic shock in the United States. J Clin Med. 2020;9(7):2094.CrossRefPubMedPubMedCentral
12.
go back to reference Nimptsch U, Busse R, Möckel M, et al. Recording early deaths following emergency department visits in inpatient data – observational study using data of 16 German hospitals. Z Evid Fortbild Qual Gesundhwes. 2023;177:35–40.CrossRefPubMed Nimptsch U, Busse R, Möckel M, et al. Recording early deaths following emergency department visits in inpatient data – observational study using data of 16 German hospitals. Z Evid Fortbild Qual Gesundhwes. 2023;177:35–40.CrossRefPubMed
15.
go back to reference Cohen RA, Terlizzi EP, Cha AE et al. National Center for Health Statistics. Health insurance coverage: early release of estimates from the national health interview survey, 2020. Baltimore, MD: Centers for Medicare & Medicaid Services. https://doi.org/10.15620/cdc:108816 Cohen RA, Terlizzi EP, Cha AE et al. National Center for Health Statistics. Health insurance coverage: early release of estimates from the national health interview survey, 2020. Baltimore, MD: Centers for Medicare & Medicaid Services. https://​doi.​org/​10.​15620/​cdc:​108816
16.
go back to reference Wilson M, Cutler D. Emergency department profits are likely to continue as the affordable care act expands coverage. Health Aff (Millwood). 2014;33(5):792–9.CrossRefPubMed Wilson M, Cutler D. Emergency department profits are likely to continue as the affordable care act expands coverage. Health Aff (Millwood). 2014;33(5):792–9.CrossRefPubMed
21.
go back to reference Krumholz HM, Wang Y, Mattera JA, et al. An administrative claims model suitable for profiling hospital performance based on 30-day mortality rates among patients with an acute myocardial infarction. Circulation. 2006;113(13):1683–92.CrossRefPubMed Krumholz HM, Wang Y, Mattera JA, et al. An administrative claims model suitable for profiling hospital performance based on 30-day mortality rates among patients with an acute myocardial infarction. Circulation. 2006;113(13):1683–92.CrossRefPubMed
23.
go back to reference Nimptsch U, Busse R. [ST-elevation myocardial infarction and percutaneous coronary intervention: analysis of Time Stamps in Hospital Administrative Data]. Gesundheitswesen. 2021;83(S 02):S122–9.PubMed Nimptsch U, Busse R. [ST-elevation myocardial infarction and percutaneous coronary intervention: analysis of Time Stamps in Hospital Administrative Data]. Gesundheitswesen. 2021;83(S 02):S122–9.PubMed
25.
go back to reference Benchimol EI, Smeeth L, Guttmann A, the RECORD Working Committee, et al. The REporting of studies conducted using observational routinely-collected health data (RECORD) statement. PLoS Med. 2015;12(10):e1001885.CrossRefPubMedPubMedCentral Benchimol EI, Smeeth L, Guttmann A, the RECORD Working Committee, et al. The REporting of studies conducted using observational routinely-collected health data (RECORD) statement. PLoS Med. 2015;12(10):e1001885.CrossRefPubMedPubMedCentral
27.
go back to reference Carinci F, Van Gool K, Mainz J, OECD Health Care Quality Indicators Expert Group, et al. Towards actionable international comparisons of health system performance: expert revision of the OECD framework and quality indicators. Int J Qual Health Care. 2015;27(2):137–46.PubMed Carinci F, Van Gool K, Mainz J, OECD Health Care Quality Indicators Expert Group, et al. Towards actionable international comparisons of health system performance: expert revision of the OECD framework and quality indicators. Int J Qual Health Care. 2015;27(2):137–46.PubMed
28.
go back to reference André R, Bongard V, Elosua R, et al. International differences in acute coronary syndrome patients’ baseline characteristics, clinical management and outcomes in Western Europe: the EURHOBOP study. Heart. 2014;100(15):1201–7.CrossRefPubMed André R, Bongard V, Elosua R, et al. International differences in acute coronary syndrome patients’ baseline characteristics, clinical management and outcomes in Western Europe: the EURHOBOP study. Heart. 2014;100(15):1201–7.CrossRefPubMed
29.
go back to reference Bottle A, Middleton S, Kalkman CJ, Livingston EH, Aylin P. Global comparators project: international comparison of hospital outcomes using administrative data. Health Serv Res. 2013;48(6 Pt 1):2081–100.CrossRefPubMedPubMedCentral Bottle A, Middleton S, Kalkman CJ, Livingston EH, Aylin P. Global comparators project: international comparison of hospital outcomes using administrative data. Health Serv Res. 2013;48(6 Pt 1):2081–100.CrossRefPubMedPubMedCentral
30.
go back to reference Maier B, Loewe A, Larscheid P, et al. Out-of-hospital and in-hospital death from myocardial infarction in Berlin. Gesundheitswesen. 2021;83(4):291–6.PubMed Maier B, Loewe A, Larscheid P, et al. Out-of-hospital and in-hospital death from myocardial infarction in Berlin. Gesundheitswesen. 2021;83(4):291–6.PubMed
31.
go back to reference Goldberg RJ, Glatfelter K, Burbank-Schmidt E, et al. Trends in community mortality due to coronary heart disease. Am Heart J. 2006;151(2):501–7.CrossRefPubMed Goldberg RJ, Glatfelter K, Burbank-Schmidt E, et al. Trends in community mortality due to coronary heart disease. Am Heart J. 2006;151(2):501–7.CrossRefPubMed
33.
go back to reference Ebeling M, Mühlichen M, Talbäck M, et al. Disease incidence and not case fatality drives the rural disadvantage in myocardial-infarction-related mortality in Germany. Prev Med. 2024;179:107833.CrossRefPubMed Ebeling M, Mühlichen M, Talbäck M, et al. Disease incidence and not case fatality drives the rural disadvantage in myocardial-infarction-related mortality in Germany. Prev Med. 2024;179:107833.CrossRefPubMed
34.
go back to reference Groene O, Kristensen S, Arah OA, DUQuE Project Consortium, et al. Feasibility of using administrative data to compare hospital performance in the EU. Int J Qual Health Care. 2014;26(Suppl 1):108–15.CrossRefPubMedPubMedCentral Groene O, Kristensen S, Arah OA, DUQuE Project Consortium, et al. Feasibility of using administrative data to compare hospital performance in the EU. Int J Qual Health Care. 2014;26(Suppl 1):108–15.CrossRefPubMedPubMedCentral
Metadata
Title
Impact of early death recording on international comparison of acute myocardial infarction mortality – administrative hospital data study using the example of Germany and the United States
Authors
Ulrike Nimptsch
Thomas Mansky
Reinhard Busse
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2024
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/s12913-024-11044-6

Other articles of this Issue 1/2024

BMC Health Services Research 1/2024 Go to the issue