Skip to main content
Top
Published in: Indian Journal of Otolaryngology and Head & Neck Surgery 2/2019

01-11-2019 | Clinical Report

Myeloid Sarcoma of Temporal Bone: A Rare Manifestation of Relapse Acute Myeloid Leukemia

Authors: Bee See Goh, Chian Ling Tang, Geok Chin Tan

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Special Issue 2/2019

Login to get access

Abstract

Myeloid sarcoma is a rare malignant extramedullary neoplasm of myeloid precursor cells. This disorder may occur in concomitance with or precede development of acute or chronic myeloid leukemia. Sometimes, it is the initial manifestation of relapse in a previously treated acute myeloid leukemia. We report a case of 11 years old boy with acute myeloid leukemia in remission state, presented with short history of right otalgia associated with facial nerve palsy. Diagnosis of right acute mastoiditis with facial nerve palsy as complication of acute otitis media was made initially. Patient underwent simple cortical mastoidectomy but histopathology from soft tissue that was sent revealed diagnosis of myeloid sarcoma. A leukemic relapse was confirmed by paediatric oncologist through bone marrow biopsy. Chemotherapy was commenced but patient responded poorly to the treatment.
Literature
1.
go back to reference Jaffe ES, Harris NL, Stein H, Vardiman JW (2001) Pathology and genetics. Tumours of haematopoietic and lymphoid tissues. IARC Press, Lyon, pp 104–105 Jaffe ES, Harris NL, Stein H, Vardiman JW (2001) Pathology and genetics. Tumours of haematopoietic and lymphoid tissues. IARC Press, Lyon, pp 104–105
2.
go back to reference Pileri SA et al (2007) Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia 21(2):340–350CrossRef Pileri SA et al (2007) Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia 21(2):340–350CrossRef
3.
go back to reference Dusenbery KE, Howells WB, Arthur DC, Alonzo T, Lee JW, Kobrinsky N, Barnard DR, Wells RJ, Buckley JD, Lange BJ, Woods WG (2003) Extramedullary leukemia in children with newly diagnosed acute myeloid leukemia: a report from the Children’s Cancer Group. J Pediatr Hematol Oncol 25(10):760–768CrossRef Dusenbery KE, Howells WB, Arthur DC, Alonzo T, Lee JW, Kobrinsky N, Barnard DR, Wells RJ, Buckley JD, Lange BJ, Woods WG (2003) Extramedullary leukemia in children with newly diagnosed acute myeloid leukemia: a report from the Children’s Cancer Group. J Pediatr Hematol Oncol 25(10):760–768CrossRef
4.
go back to reference Joseph DE, Durosinmi MA (2008) Neurological complications of chronic myeloid leukaemia: any cure? Niger J Clin Pract 11(3):246–249PubMed Joseph DE, Durosinmi MA (2008) Neurological complications of chronic myeloid leukaemia: any cure? Niger J Clin Pract 11(3):246–249PubMed
5.
go back to reference Todd NW Jr, Bowman CA (1984) Acute myelogenous leukemia presenting as atypical mastoiditis with facial paralysis. Int J Pediatr Otorhinolaryngol 7(2):173–177CrossRef Todd NW Jr, Bowman CA (1984) Acute myelogenous leukemia presenting as atypical mastoiditis with facial paralysis. Int J Pediatr Otorhinolaryngol 7(2):173–177CrossRef
6.
go back to reference Berlinger NT, Koutroupas S, Adams G, Maisel R (1980) Patterns of involvement of the temporal bone in metastatic and systemic malignancy. Laryngoscope 90(4):619–627CrossRef Berlinger NT, Koutroupas S, Adams G, Maisel R (1980) Patterns of involvement of the temporal bone in metastatic and systemic malignancy. Laryngoscope 90(4):619–627CrossRef
7.
go back to reference Chang KH, Kim DK, Jun BC, Park YS (2009) Temporal bone myeloid sarcoma. Clin Exp Otorhinolaryngol 2(4):198–202CrossRef Chang KH, Kim DK, Jun BC, Park YS (2009) Temporal bone myeloid sarcoma. Clin Exp Otorhinolaryngol 2(4):198–202CrossRef
8.
go back to reference Noh BW, Park SW, Chun JE, Kim JH, Kim HJ, Lim MK (2009) Granulocytic sarcoma in the head and neck: CT and MR imaging findings. Clin Exp Otorhinolaryngol 2(2):66–71CrossRef Noh BW, Park SW, Chun JE, Kim JH, Kim HJ, Lim MK (2009) Granulocytic sarcoma in the head and neck: CT and MR imaging findings. Clin Exp Otorhinolaryngol 2(2):66–71CrossRef
9.
go back to reference Yamauchi K, Yasuda M (2002) Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature. Cancer 94(6):1739–1746CrossRef Yamauchi K, Yasuda M (2002) Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature. Cancer 94(6):1739–1746CrossRef
Metadata
Title
Myeloid Sarcoma of Temporal Bone: A Rare Manifestation of Relapse Acute Myeloid Leukemia
Authors
Bee See Goh
Chian Ling Tang
Geok Chin Tan
Publication date
01-11-2019
Publisher
Springer India
Published in
Indian Journal of Otolaryngology and Head & Neck Surgery / Issue Special Issue 2/2019
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-015-0930-8

Other articles of this Special Issue 2/2019

Indian Journal of Otolaryngology and Head & Neck Surgery 2/2019 Go to the issue