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Environmental Health and Preventive Medicine

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01-05-2015 | Review

Mutagenic and carcinogenic actions of chromium and its compounds

Authors: Arstan Abdramanovich Mamyrbaev, Timur Agataevich Dzharkenov, Zina Amangalievna Imangazina, Umit Abulkhairovna Satybaldieva

Published in: Environmental Health and Preventive Medicine | Issue 3/2015

Abstract

Numerous experimental observations have been made on microorganisms and culture of the cells of mammals as well as the accounting of the chromosomal aberrations in the bone marrow cells of the mammals and of human cells displayed that the chromium and its compounds possess a pronounced mutagenic effect. Translocation test, induction record of DNA damage and repair systems in the mammalian and human cells with greater precision proves the presence of the mutagenic effect of the chromium and its compounds, which in turn is dependent on dose and time of this metal intoxication. Chromium and its compounds have pronounced mutagenic effect, on increased admission to organism of mammals and protozoa.

WHO. Assessment of carcinogenicity and mutagenicity of chemical compounds. WHO Scientific Group. WHO Technical Report Series 1975; 546:24.

Adler J. Germ cell sensitivity in mammals. In: mutagens in our environment: proceedings of the 12th annual meeting of the European Environmental Mutagen Society, Espoo, Finland, June 20–24, 1982. p. 137–148.

Bondarenko VM, Karunnikova MM. The lethal and mutagenic action of chromium compounds on bacteria. In: Clinic, diagnosis and treatment of chromium toxicity and sensitization. Aktubinsk; 1981. p. 131–137.

Bigaliyev AB, Bakiyev IS. Mutagenicity studies of chromium on D. Melanogaster by DLM, message 1. Dependence of DLM frequency on the concentration of potassium dichromate and duration of exposure. In: Clinic, diagnosis and treatment of chromium intoxication and sensitization. Aktubinsk; 1981. p. 115–117.

Bakiyev IS, Turetaeva AD. Mutagenicity studies on D. Melanogaster chromium by DLM, message 2. Comparative analysis of DLM frequency under the action of 3- and 6-valent chromium compounds. In: Clinic, diagnosis and treatment of chromium intoxication and sensitization. Aktubinsk; 1981. p. 122–125.

Khesin YaS. Dimensions of the nuclei and cell functions. Science, 1967. p. 487.

Bochkov NP. Mutagenesis of humans. Bull Med Sci USSR. 1976;7:47–53.

Minseitova SR, Dzhusupkalieva MM. Efficiency of displacement of transposon Tn 1 and Tn 9 under the action of chromium compounds and boron. In: Clinical and hygienic aspects of the effect of chromium and other chemicals on the organism. Part 1. Aktubinsk; 1990. p. 99–101.

Bakiyev IS, Minseitova SR, Dzhusupkalieva MM. Study of long-term effects of the mutagenic effect of potassium dichromate in the experiment. In: Clinical and hygienic aspects of the effect of chromium and other chemicals on the organism. Part 1. Aktubinsk; 1990. p. 96–98.

10.

Gogua ML. Study of the genotoxic potential of chromium, molybdenum, tungsten salts, on floral test systems. Author's abstract, 2003. p. 24.

11.

Belezin SL, Saychenko SP. Features of combined mutagenic effect of chromium and manganese on the model of microbial mutations. Hyg Sanit. 1988;12:22–4.

12.

Elemesova MSH. The study of the cytological and cytogenetic activity of chromic anhydride on rats. In: Clinic, diagnosis and treatment of chromium intoxication and sensitization. Aktubinsk; 1981. p. 117–120.

13.

Patin Y, Kozachenko VI. The mutagenic activity of chromium compounds. Hyg Sanit. 1981;5:46–9.

14.

Bigaliyev AB. Cytogenetic study in vivo of mutagenic features of chromium compounds. In: Genetic consequences of environmental pollution. Nauka; 1977. p. 173–176.

15.

Bigaliyev AB. Genetic effects of heavy metal ions. Alma-Ata, 1986. p. 178.

16.

Elias Z, Schneider O, Aubry F, Daniere MC, Poirot O. Sister chromatid exchanges in Chinese hamster V79 cells treated with the trivalent chromium compounds, chromic chloride and chromic oxide. Carcinogenesis. 1983;4:604–11.CrossRef

17.

Sarto F, Cominato I, Bianchi V, Levis AG. Increased incidence of chromosomal aberration and sister chromatid exchanges in workers exposed to chromic acid (CrO₃) in electroplating factories. Carcinogenesis. 1982;3:1011–6.CrossRefPubMed

18.

Bronzetti G, Galli A, Boccardo P, Del Carratore R, Edel J, Sabbioni E. Genetic effects of trivalent chromium on Saccharomyces cerevisiae. Sci Total Environ. 1988;71:3–570.CrossRef

19.

Snow ET, Xu L-S. Effects of chromium (III) on DNA replication in vitro. Biol Trase Elem Rep. 1989;21:61–71.CrossRef

20.

Bigaliyev AB, Turebaev MN, Bigalieva RK, Elemesova MSH. Cytogenetic examination of persons engaged in the production of chrome. Genetics. 1977;13(3):545–7.

21.

Azhayev SA. Sister chromatid exchanges in lymphocytes of workers of chrome production. In: Clinical features, diagnosis and treatment of chromium toxicity and sensitization. Aktubinsk; 1981. p. 70–71.

22.

Azhayev SA. Comparative evaluation of chromosomal aberrations and sister chromatid exchanges in lymphocytes of persons exposed to chromium. In: Clinic, diagnosis and treatment of chromium intoxication and sensitization. Aktubinsk; 1981. p. 120–121.

23.

Bianchi V, Celotti L. Sensibilizzazione di cellule di hamster in colturamediantetrattementiripetuti con bicromatopotassio. Bull Zool. 1975;42(4):435–6.

24.

Bianchi V, Levis AG. Review of genetic effects and mechanisms of action of chromium compounds. Sci Total Environ. 1988;71(3):351–5.CrossRefPubMed

25.

Bronca M, Dessi A, Koziovski H, Micera G, Serra MV. In vitro interaction of mutagenic chromium (VI) with red blood cells. FEBS Lett. 1989;257(1):14–6.

26.

Elias Z, Poirot O, Schneider O, Daniere MC, Terzetti F, Yuedenet JC, Cavelier C. Cellular uptake, cytotoxic and mutagenic effects of insoluble chromic oxide in V79 Chinese hamster cells. Mutat Res. 1986;169:159–70.CrossRefPubMed

27.

Fradkin A, Janoff A, Loune BP, Kuschner M. In vitro transformation of BHK 21 cells grown in the presence of calcium chromate. Cancer Res. 1975;35:1058–63.PubMed

28.

Palierao SR, Landolph SR. Soluble insoluble hexavalent chromate. Relationship of mutation to in vitro transformation and particle uptake. Biol Traseelem Res. 1989;21:469–74.

29.

Tsuda H, Kato K. Chromosome aberrations and morphological transformation in hamster embryonic cells treated with potassium dichromate in vitro. Mutat Res. 1977;46(2):87–94.CrossRefPubMed

30.

Venit S, Levy LS. Mutagenicity of chromates in bacteria and its relevance to chromate carcinogenesis. Nature. 1974;250:493–5.CrossRef

31.

Farell RP, Jbdd RS, Lay PA, Dixon NE, Baker RS, Bonin AM. Chromium (V) induced cleavage of DNA: are chromium (V) complexes in chromium (V)—induced cancers. Chem Res Toxicol. 1989;2(4):227–9.CrossRef

32.

Fornase AJ, Seres DS, Lechner JF, Harris CC. DNA-protein crosslinking by chromium salts. Chem-Biol Interact. 1981;36:345–54.CrossRef

33.

Gao M, Snow E, Sing J, Zhikovich A, Costa M. Unlike chromium (III) alone, low concentrations of amino acid-chromium (III)-DNA-crosslinks act as strong blocks to DNA replications: Abstr Environ Mutagen Soc: 26th Annu Mut. 1995.

34.

Gomez Arroyo S, Aitmarino M, Villalobes-Pietrini R. Sister chromatids exchanges induced by some chromium compounds in human lymphocytes in vitro. Mutat Res. 1981;90:425.CrossRefPubMed

35.

Hamilton JW, Weterhahn KE. Differential effects of chromium (VI) on constitutive and inducible gene expression with chromium (VI) induced DNA damage. Carcinogenesis. 1989;2(5):274–86.CrossRef

36.

Rainaldi G, Colella CM, Pirs A, Mariana I. Thioguanine resistance, ovabain resistance and sister chromatid exchanges in V 79/AP4 XHO treated with potassium dichromate. Chem Biol Interact. 1982;42:45.CrossRefPubMed

37.

Bochkov NP, Demin YUS, Luchnic NV. Classification and accounting methods of chromosomal aberrations in somatic cells. Genetics. 1972;8(5):133–41.

38.

Bochkov NP. Medical and biological approaches to cytogenetic monitoring of human population. In: Liss AR editor. Mutagens in our environment. Espoo; 1982. p. 101–109.

39.

Alov IA. Problem of pathology of mitosis. Results of science and technology. Cytology. VINITI. 1976;3:40–65.

40.

Sanotsky IV, Fomenko VN. The long-term consequences of the effects of chemicals on the organism. Medicine. Moscow, 1979. p. 230.

41.

Chaubey RC, Kavi BR, Chauhen PS, Sundaram K. The evaluation of micronucleus test as an “in vitro” cytogenetic technique in mouse. Mutat Res. 1978;53(2):164–76.CrossRef

Title: Mutagenic and carcinogenic actions of chromium and its compounds
Authors: Arstan Abdramanovich Mamyrbaev
Timur Agataevich Dzharkenov
Zina Amangalievna Imangazina
Umit Abulkhairovna Satybaldieva
Publication date: 01-05-2015
Publisher: Springer Japan
Published in: Environmental Health and Preventive Medicine / Issue 3/2015
Print ISSN: 1342-078X
Electronic ISSN: 1347-4715
DOI: https://doi.org/10.1007/s12199-015-0458-2

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Mutagenic and carcinogenic actions of chromium and its compounds

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