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Open Access 01-12-2021 | Musculoskeletal Pain | Review

Juvenile primary Fibromyalgia Syndrome: epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis

Authors: Maya Levy Coles, Rotem Weissmann, Yosef Uziel

Published in: Pediatric Rheumatology | Issue 1/2021

Abstract

Juvenile primary fibromyalgia syndrome (JPFS) is a chronic, musculoskeletal pain syndrome affecting children and adolescents, most commonly adolescent girls. The syndrome has a multifactorial etiology, with altered central pain processing playing an important role. The hallmark symptom is severe, widespread musculoskeletal pain. Other symptoms include sleep and mood disturbances, headaches, stiffness, and subjective joint swelling. Physical examination can reveal multiple tender points. The diagnosis is clinical, with defined criteria. Early diagnosis and intervention are important. In this part of the review, we discuss the epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis of JPFS. Part two will focus on treatment and prognosis.

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Title: Juvenile primary Fibromyalgia Syndrome: epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis
Authors: Maya Levy Coles
Rotem Weissmann
Yosef Uziel
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Musculoskeletal Pain
Fibromyalgia
Fibromyalgia
Published in: Pediatric Rheumatology / Issue 1/2021
Electronic ISSN: 1546-0096
DOI: https://doi.org/10.1186/s12969-021-00493-6

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Juvenile primary Fibromyalgia Syndrome: epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis

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Keynote webinar | Spotlight on medication adherence

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Blau syndrome: a case report from Palestine

Community poverty level influences time to first pediatric rheumatology appointment in Polyarticular Juvenile Idiopathic Arthritis

Severe COVID-19 in pediatric age: an update on the role of the anti-rheumatic agents

Lung clearance index and diffusion capacity for CO to detect early functional pulmonary impairment in children with rheumatic diseases

Clinical and genetic characteristics of PSTPIP1-associated myeloid-related proteinemia inflammatory syndrome