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Open Access 01-12-2022 | Muscular Dystrophy | Review

Management of arthrofibrosis in neuromuscular disorders: a review

Authors: Edith Martinez-Lozano, Indeevar Beeram, Diana Yeritsyan, Mark W. Grinstaff, Brian D. Snyder, Ara Nazarian, Edward K. Rodriguez

Published in: BMC Musculoskeletal Disorders | Issue 1/2022

Abstract

Arthrofibrosis, or rigid contracture of major articular joints, is a significant morbidity of many neurodegenerative disorders. The pathogenesis depends on the mechanism and severity of the precipitating neuromuscular disorder. Most neuromuscular disorders, whether spastic or hypotonic, culminate in decreased joint range of motion. Limited range of motion precipitates a cascade of pathophysiological changes in the muscle-tendon unit, the joint capsule, and the articular cartilage. Resulting joint contractures limit functional mobility, posing both physical and psychosocial burdens to patients, economic burdens on the healthcare system, and lost productivity to society. This article reviews the pathophysiology of arthrofibrosis in the setting of neuromuscular disorders. We describe current non-surgical and surgical interventions for treating arthrofibrosis of commonly affected joints. In addition, we preview several promising modalities under development to ameliorate arthrofibrosis non-surgically and discuss limitations in the field of arthrofibrosis secondary to neuromuscular disorders.

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Title: Management of arthrofibrosis in neuromuscular disorders: a review
Authors: Edith Martinez-Lozano
Indeevar Beeram
Diana Yeritsyan
Mark W. Grinstaff
Brian D. Snyder
Ara Nazarian
Edward K. Rodriguez
Publication date: 01-12-2022
Publisher: BioMed Central
Keywords: Muscular Dystrophy
Muscular Dystrophy
Published in: BMC Musculoskeletal Disorders / Issue 1/2022
Electronic ISSN: 1471-2474
DOI: https://doi.org/10.1186/s12891-022-05677-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Management of arthrofibrosis in neuromuscular disorders: a review

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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