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Current Sleep Medicine Reports
Published in: Current Sleep Medicine Reports 1/2023

01-03-2023 | Multiple Sleep Latency Test | HYPERSOMNIA DISORDERS (D PLANTE, SECTION EDITOR)

Novel Objective Measures of Hypersomnolence

Authors: Alex Dworetz, Lynn Marie Trotti, Surina Sharma

Published in: Current Sleep Medicine Reports | Issue 1/2023

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Abstract 

Purpose of Review

The purpose is to provide a brief overview of current objective measures of hypersomnolence, discuss proposed measure modifications, and review emerging measures.

Recent Findings

There is potential to optimize current tools using novel metrics. High-density and quantitative EEG-based measures may provide discriminative informative. Cognitive testing may quantify cognitive dysfunction common to hypersomnia disorders, particularly in attention, and objectively measure pathologic sleep inertia. Structural and functional neuroimaging studies in narcolepsy type 1 have shown considerable variability but so far implicate both hypothalamic and extra-hypothalamic regions; fewer studies of other CDH have been performed. There is recent renewed interest in pupillometry as a measure of alertness in the evaluation of hypersomnolence.

Summary

No single test captures the full spectrum of disorders, and use of multiple measures will likely improve diagnostic precision. Research is needed to identify novel measures and disease-specific biomarkers and to define combinations of measures optimal for CDH diagnosis.
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Metadata
Title
Novel Objective Measures of Hypersomnolence
Authors
Alex Dworetz
Lynn Marie Trotti
Surina Sharma
Publication date
01-03-2023
Publisher
Springer International Publishing
Published in
Current Sleep Medicine Reports / Issue 1/2023
Electronic ISSN: 2198-6401
DOI
https://doi.org/10.1007/s40675-022-00245-2

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