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01-02-2018 | CLINICOPATHOLOGICAL CONFERENCE

Multiple Opportunistic Infections in an 8-month-old Infant: Is it Seronegative HIV Infection?

Authors: Uma Nahar Saikia, Aman Gupta, Abin Koshy, Saniya Gupta

Published in: Indian Journal of Pediatrics | Issue 2/2018

Abstract

We describe an 8-mo-old boy who presented with acute respiratory failure following a prolonged febrile respiratory illness with features suggesting immunodeficiency.

Enormous Gains, Persistent Challenges. In: Global AIDS Update. 2016. Available at: http://www.unaids.org/en/resources/documents/2016/Global-AIDS-update-2016. Accessed 18 July 2016.

Number of children (<15 years) receiving ART globally, and by WHO region, 2000-2015. In: Children receiving ART by WHO region, 2000-2015. Available at: www.who.int/hiv/data/pedartregions2016.png?ua=1. Accessed 25 Aug 2016.

Role of CD4+ T lymphocytes in Disease Progression. In: National Guidelines for Enumeration of CD4. 2015. Available at: http://naco.gov.in/upload/2015%20MSLNS/CD4Guidelines.pdf. Accessed 25 Aug 2016.

Opportunistic Infections in HIV Infected Children. In: Pediatric Antiretroviral Therapy (ART) Guidelines. 2013. Available at: http://naco.gov.in/upload/2014%20mslns/CST/Pediatric_14-03-2014.pdf. Accessed 25 Aug 2016.

Huang L, Hecht FM, Stansell JD, Montanti R, Hadley WK, Hopewell PC. Suspected pneumocystis carinii pneumonia with a negative induced sputum examination: is early bronchoscopy useful? Am J Respir Crit Care Med. 1995;151:1866–71.CrossRefPubMed

Larsen HH, Huang L, Kovacs JA, et al. A prospective, blinded study of quantitative touch-down polymerase chain reaction using oral-wash samples for diagnosis of pneumocystis pneumonia in HIV infected patients. J Infect Dis. 2004;189:1679–83.CrossRefPubMed

Mylonakis E, Paliou M, Lally M, Flanigan TP, Rich JD. Laboratory testing for infection with the human immunodeficiency virus: established and novel approaches. Am J Med. 2000;109:568–76.CrossRefPubMed

Quinonez JM, Begue RE, Steele RW. HIV seronegativity in an infant with the acquired immunodeficiency syndrome. South Med J. 1998;91:879–81.PubMed

Chin BS, Lee SH, Kim GJ, Kee MK, Suh SD, Kim SS. Early identification of seronegative human immunodeficiency virus type 1 infection with severe presentation. J Clin Microbiol. 2007;45:1659–62.CrossRefPubMedPubMedCentral

10.

Spivak AM, Brennan T, O’Connell K, et al. A case of seronegative HIV-1 infection. J Infect Dis. 2010;201:341–5.CrossRefPubMedPubMedCentral

11.

Zouhair S, Roussin-Bretagne S, Moreau A, et al. Group o human immunodeficiency virus type 1 infection that escaped detection in two immmunoassays. J Clin Microbiol. 2006;44:662–5.CrossRefPubMedPubMedCentral

12.

Loussert-Ajaka I, Ly TD, Chaix ML, et al. HIV-1/HIV-2 seronegativity in HIV-1 subtype O infected patients. Lancet. 1994;343:1393–4.CrossRefPubMed

13.

Hare CB, Pappalardo BL, Busch MP, et al. Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection. Clin Infect Dis. 2006;42:700–8.CrossRefPubMed

14.

Quijano G, Siminovich M, Drut R. Histopathologic findings in the lymphoid and reticuloendothelial system in pediatric HIV infection: a post-mortem study. Pediatr Pathol Lab Med. 1997;17:845–56.PubMed

15.

De Rossi A, Giaquinto C, Del Mistro A, Zamarchi R, Chieco-Bianchi L. Onset of HIV-1 antibody production after highly active antiretroviral therapy in a seronegative HIV-1-infected child. AIDS. 2000;14:1284–6.CrossRefPubMed

Title: Multiple Opportunistic Infections in an 8-month-old Infant: Is it Seronegative HIV Infection?
Authors: Uma Nahar Saikia
Aman Gupta
Abin Koshy
Saniya Gupta
Publication date: 01-02-2018
Publisher: Springer India
Published in: Indian Journal of Pediatrics / Issue 2/2018
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-017-2461-7

At a glance: The STEP trials

Springer Medicine

Multiple Opportunistic Infections in an 8-month-old Infant: Is it Seronegative HIV Infection?

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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