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Published in: BMC Psychiatry 1/2010

Open Access 01-12-2010 | Research article

Multiple barriers against successful care provision for depressed patients in general internal medicine in a Japanese rural hospital: a cross-sectional study

Authors: Tsuyuka Ohtsuki, Masatoshi Inagaki, Yuetsu Oikawa, Akiyoshi Saitoh, Mie Kurosawa, Kumiko Muramatsu, Mitsuhiko Yamada

Published in: BMC Psychiatry | Issue 1/2010

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Abstract

Background

A general internist has an important role in primary care, especially for the elderly in rural areas of Japan. Although effective intervention models for depressed patients in general practice and primary care settings have been developed in the US and UK medical systems, there is little information regarding even the recognition rate and prescription rate of psychotropic medication by general internists in Japan. The present study surveyed these data cross-sectionally in a general internal medicine outpatient clinic of a Japanese rural hospital.

Methods

Patients were consecutively recruited and evaluated for major depressive disorder or any mood disorder using the Patient Health Questionnaire (PHQ). Physicians who were blinded to the results of the PHQ were asked to diagnose whether the patients had any mental disorders, and if so, whether they had mood disorders or not. Data regarding prescription of psychotropic medicines were collected from medical records.

Results

Among 312 patients, 27 (8.7%) and 52 (16.7%) were identified with major depressive disorder and any mood disorder using the PHQ, respectively. Among those with major depressive disorder, 21 (77.8%) were recognized by physicians as having a mental disorder, but only three (11.1%) were diagnosed as having a mood disorder.
Only two patients with major depressive disorder (7.4%) had been prescribed antidepressants. Even among those (n = 15) whom physicians diagnosed with a mood disorder irrespective of the PHQ results, only four (26.7%) were prescribed an antidepressant.

Conclusions

Despite a high prevalence of depression, physicians did not often recognize depression in patients. In addition, most patients who were diagnosed by physicians as having a mood disorder were not prescribed antidepressants. Multiple barriers to providing appropriate care for depressed patients exist, such as recognizing depression, prescribing appropriate medications, and appropriately referring patients to mental health specialists.
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Literature
1.
go back to reference World Health Organization: The global burden of disease 2004 update. 2008, WHO, Geneva World Health Organization: The global burden of disease 2004 update. 2008, WHO, Geneva
3.
go back to reference Tylee A: Identifying and managing depression in primary care in the United Kingdom. J Clin Psychiatry. 2006, 67 (Suppl 6): 41-45.PubMed Tylee A: Identifying and managing depression in primary care in the United Kingdom. J Clin Psychiatry. 2006, 67 (Suppl 6): 41-45.PubMed
4.
go back to reference Wolf NJ, Hopko DR: Psychosocial and pharmacological interventions for depressed adults in primary care: a critical review. Clin Psychol Rev. 2008, 28: 131-161. 10.1016/j.cpr.2007.04.004.CrossRefPubMed Wolf NJ, Hopko DR: Psychosocial and pharmacological interventions for depressed adults in primary care: a critical review. Clin Psychol Rev. 2008, 28: 131-161. 10.1016/j.cpr.2007.04.004.CrossRefPubMed
5.
go back to reference Gilbody S, Bower P, Fletcher J, Richards D, Sutton AJ: Collaborative care for depression: a cumulative meta-analysis and review of longer-term outcomes. Arch Intern Med. 2006, 166: 2314-2321. 10.1001/archinte.166.21.2314.CrossRefPubMed Gilbody S, Bower P, Fletcher J, Richards D, Sutton AJ: Collaborative care for depression: a cumulative meta-analysis and review of longer-term outcomes. Arch Intern Med. 2006, 166: 2314-2321. 10.1001/archinte.166.21.2314.CrossRefPubMed
6.
go back to reference Kawakami N: Study on World Mental Health Japan Survey (Kokoro no kenko ni tsuite no ekigakuchosa ni kansuru kenkyu [in Japanese]). 2004-2006 A Report for the Health Labour Sciences Research Grant. 2007, The Ministry of Health Labour and Welfare Kawakami N: Study on World Mental Health Japan Survey (Kokoro no kenko ni tsuite no ekigakuchosa ni kansuru kenkyu [in Japanese]). 2004-2006 A Report for the Health Labour Sciences Research Grant. 2007, The Ministry of Health Labour and Welfare
7.
go back to reference Naganuma Y, Tachimori H, Kawakami N, Takeshima T, Ono Y, Uda H, Hata Y, Nakane Y, Nakane H, Iwata N, et al: Twelve-month use of mental health services in four areas in Japan: findings from the World Mental Health Japan Survey 2002-2003. Psychiatry Clin Neurosci. 2006, 60: 240-248. 10.1111/j.1440-1819.2006.01492.x.CrossRefPubMed Naganuma Y, Tachimori H, Kawakami N, Takeshima T, Ono Y, Uda H, Hata Y, Nakane Y, Nakane H, Iwata N, et al: Twelve-month use of mental health services in four areas in Japan: findings from the World Mental Health Japan Survey 2002-2003. Psychiatry Clin Neurosci. 2006, 60: 240-248. 10.1111/j.1440-1819.2006.01492.x.CrossRefPubMed
8.
go back to reference Government of Japan: The comprehensive suicide prevention initiative. 2007, Government of Japan, Tokyo Government of Japan: The comprehensive suicide prevention initiative. 2007, Government of Japan, Tokyo
9.
go back to reference Nakane Y, Michitsuji S: Results from the Nagasaki Center. Mental Illness in General Health Care: An International Study. Edited by: Ustun TB, Sartorius N. 1995, Chichester, UK: John Wiley & Sons, 193-209. Nakane Y, Michitsuji S: Results from the Nagasaki Center. Mental Illness in General Health Care: An International Study. Edited by: Ustun TB, Sartorius N. 1995, Chichester, UK: John Wiley & Sons, 193-209.
10.
go back to reference Ministry of Health, Labour and Welfare: The Patient Survey. Statistical Surveys conducted by Ministry of Health, Labour and Welfare. 2008, Ministry of Health, Labour and Welfare, Tokyo Ministry of Health, Labour and Welfare: The Patient Survey. Statistical Surveys conducted by Ministry of Health, Labour and Welfare. 2008, Ministry of Health, Labour and Welfare, Tokyo
11.
go back to reference Huang CQ, Dong BR, Lu ZC, Yue JR, Liu QX: Chronic diseases and risk for depression in old age: A meta-analysis of published literature. Ageing Res Rev. 2010, 9: 131-141. 10.1016/j.arr.2009.05.005.CrossRefPubMed Huang CQ, Dong BR, Lu ZC, Yue JR, Liu QX: Chronic diseases and risk for depression in old age: A meta-analysis of published literature. Ageing Res Rev. 2010, 9: 131-141. 10.1016/j.arr.2009.05.005.CrossRefPubMed
12.
go back to reference Ministry of Internal Affairs and Communications: 2005 Population Census. The Population Census. 2005, Ministry of Internal Affairs and Communications Ministry of Internal Affairs and Communications: 2005 Population Census. The Population Census. 2005, Ministry of Internal Affairs and Communications
13.
go back to reference First MB, Spitzer RL, Gibbon M, Williams JBW: Structured Clinical Interview for DSM-IV Axis I Disorders (SCID), Clinical Version. 1997, Washington DC: American Psychiatric Press First MB, Spitzer RL, Gibbon M, Williams JBW: Structured Clinical Interview for DSM-IV Axis I Disorders (SCID), Clinical Version. 1997, Washington DC: American Psychiatric Press
14.
go back to reference Muramatsu K, Miyaoka H, Kamijima K, Muramatsu Y, Yoshida M, Otsubo T, Gejyo F: The patient health questionnaire, Japanese version: validity according to the mini-international neuropsychiatric interview-plus. Psychol Rep. 2007, 101: 952-960. 10.2466/PR0.101.7.952-960.PubMed Muramatsu K, Miyaoka H, Kamijima K, Muramatsu Y, Yoshida M, Otsubo T, Gejyo F: The patient health questionnaire, Japanese version: validity according to the mini-international neuropsychiatric interview-plus. Psychol Rep. 2007, 101: 952-960. 10.2466/PR0.101.7.952-960.PubMed
15.
go back to reference Spitzer RL, Williams JB, Kroenke K, Linzer M, deGruy FV, Hahn SR, Brody D, Johnson JG: Utility of a new procedure for diagnosing mental disorders in primary care. The PRIME-MD 1000 study. JAMA. 1994, 272: 1749-1756. 10.1001/jama.272.22.1749.CrossRefPubMed Spitzer RL, Williams JB, Kroenke K, Linzer M, deGruy FV, Hahn SR, Brody D, Johnson JG: Utility of a new procedure for diagnosing mental disorders in primary care. The PRIME-MD 1000 study. JAMA. 1994, 272: 1749-1756. 10.1001/jama.272.22.1749.CrossRefPubMed
16.
go back to reference Spitzer RL, Kroenke K, Williams JB: Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. JAMA. 1999, 282: 1737-1744. 10.1001/jama.282.18.1737.CrossRefPubMed Spitzer RL, Kroenke K, Williams JB: Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. JAMA. 1999, 282: 1737-1744. 10.1001/jama.282.18.1737.CrossRefPubMed
17.
go back to reference Kroenke K, Spitzer RL, Williams JB: The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001, 16: 606-613. 10.1046/j.1525-1497.2001.016009606.x.CrossRefPubMedPubMedCentral Kroenke K, Spitzer RL, Williams JB: The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001, 16: 606-613. 10.1046/j.1525-1497.2001.016009606.x.CrossRefPubMedPubMedCentral
18.
go back to reference Wittkampf KA, Naeije L, Schene AH, Huyser J, van Weert HC: Diagnostic accuracy of the mood module of the Patient Health Questionnaire: a systematic review. Gen Hosp Psychiatry. 2007, 29: 388-395. 10.1016/j.genhosppsych.2007.06.004.CrossRefPubMed Wittkampf KA, Naeije L, Schene AH, Huyser J, van Weert HC: Diagnostic accuracy of the mood module of the Patient Health Questionnaire: a systematic review. Gen Hosp Psychiatry. 2007, 29: 388-395. 10.1016/j.genhosppsych.2007.06.004.CrossRefPubMed
19.
go back to reference Gilbody S, Richards D, Brealey S, Hewitt C: Screening for depression in medical settings with the Patient Health Questionnaire (PHQ): a diagnostic meta-analysis. J Gen Intern Med. 2007, 22: 1596-1602. 10.1007/s11606-007-0333-y.CrossRefPubMedPubMedCentral Gilbody S, Richards D, Brealey S, Hewitt C: Screening for depression in medical settings with the Patient Health Questionnaire (PHQ): a diagnostic meta-analysis. J Gen Intern Med. 2007, 22: 1596-1602. 10.1007/s11606-007-0333-y.CrossRefPubMedPubMedCentral
20.
go back to reference Spitzer RL, Kroenke K, Williams JB, Lowe B: A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006, 166: 1092-1097. 10.1001/archinte.166.10.1092.CrossRefPubMed Spitzer RL, Kroenke K, Williams JB, Lowe B: A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006, 166: 1092-1097. 10.1001/archinte.166.10.1092.CrossRefPubMed
21.
go back to reference Muramatsu K, Muramatsu Y, Miyaoka H, Fuse K, Yoshimine Fi, Hosaka M, Katagiri A, Kutsumi R: Validation and utility of a japanese version of the GAD-7. PANMINERVA MEDICA 20th World Congress on Pyschosomatic Medicine Abstructs Book. 2009, 51 (Suppl 1 to No 3): 79- Muramatsu K, Muramatsu Y, Miyaoka H, Fuse K, Yoshimine Fi, Hosaka M, Katagiri A, Kutsumi R: Validation and utility of a japanese version of the GAD-7. PANMINERVA MEDICA 20th World Congress on Pyschosomatic Medicine Abstructs Book. 2009, 51 (Suppl 1 to No 3): 79-
22.
go back to reference Mitchell AJ, Vaze A, Rao S: Clinical diagnosis of depression in primary care: a meta-analysis. Lancet. 2009, 374: 609-619. 10.1016/S0140-6736(09)60879-5.CrossRefPubMed Mitchell AJ, Vaze A, Rao S: Clinical diagnosis of depression in primary care: a meta-analysis. Lancet. 2009, 374: 609-619. 10.1016/S0140-6736(09)60879-5.CrossRefPubMed
23.
go back to reference Kawakami N, Takeshima T, Ono Y, Uda H, Hata Y, Nakane Y, Nakane H, Iwata N, Furukawa TA, Kikkawa T: Twelve-month prevalence, severity, and treatment of common mental disorders in communities in Japan: preliminary finding from the World Mental Health Japan Survey 2002-2003. Psychiatry Clin Neurosci. 2005, 59: 441-452. 10.1111/j.1440-1819.2005.01397.x.CrossRefPubMed Kawakami N, Takeshima T, Ono Y, Uda H, Hata Y, Nakane Y, Nakane H, Iwata N, Furukawa TA, Kikkawa T: Twelve-month prevalence, severity, and treatment of common mental disorders in communities in Japan: preliminary finding from the World Mental Health Japan Survey 2002-2003. Psychiatry Clin Neurosci. 2005, 59: 441-452. 10.1111/j.1440-1819.2005.01397.x.CrossRefPubMed
24.
go back to reference Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, Rush AJ, Walters EE, Wang PS, National Comorbidity Survey Replication: The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA. 2003, 289: 3095-3105. 10.1001/jama.289.23.3095.CrossRefPubMed Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, Rush AJ, Walters EE, Wang PS, National Comorbidity Survey Replication: The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA. 2003, 289: 3095-3105. 10.1001/jama.289.23.3095.CrossRefPubMed
25.
go back to reference Fournier JC, DeRubeis RJ, Hollon SD, Dimidjian S, Amsterdam JD, Shelton RC, Fawcett J: Antidepressant drug effects and depression severity: a patient-level meta-analysis. JAMA. 2010, 303: 47-53. 10.1001/jama.2009.1943.CrossRefPubMedPubMedCentral Fournier JC, DeRubeis RJ, Hollon SD, Dimidjian S, Amsterdam JD, Shelton RC, Fawcett J: Antidepressant drug effects and depression severity: a patient-level meta-analysis. JAMA. 2010, 303: 47-53. 10.1001/jama.2009.1943.CrossRefPubMedPubMedCentral
26.
go back to reference Norton J, De Roquefeuil G, Boulenger JP, Ritchie K, Mann A, Tylee A: Use of the PRIME-MD Patient Health Questionnaire for estimating the prevalence of psychiatric disorders in French primary care: comparison with family practitioner estimates and relationship to psychotropic medication use. Gen Hosp Psychiatry. 2007, 29: 285-293. 10.1016/j.genhosppsych.2007.02.005.CrossRefPubMed Norton J, De Roquefeuil G, Boulenger JP, Ritchie K, Mann A, Tylee A: Use of the PRIME-MD Patient Health Questionnaire for estimating the prevalence of psychiatric disorders in French primary care: comparison with family practitioner estimates and relationship to psychotropic medication use. Gen Hosp Psychiatry. 2007, 29: 285-293. 10.1016/j.genhosppsych.2007.02.005.CrossRefPubMed
27.
go back to reference Lyness JM, Caine ED, King DA, Cox C, Yoediono Z: Psychiatric disorders in older primary care patients. J Gen Intern Med. 1999, 14: 249-254. 10.1046/j.1525-1497.1999.00326.x.CrossRefPubMedPubMedCentral Lyness JM, Caine ED, King DA, Cox C, Yoediono Z: Psychiatric disorders in older primary care patients. J Gen Intern Med. 1999, 14: 249-254. 10.1046/j.1525-1497.1999.00326.x.CrossRefPubMedPubMedCentral
Metadata
Title
Multiple barriers against successful care provision for depressed patients in general internal medicine in a Japanese rural hospital: a cross-sectional study
Authors
Tsuyuka Ohtsuki
Masatoshi Inagaki
Yuetsu Oikawa
Akiyoshi Saitoh
Mie Kurosawa
Kumiko Muramatsu
Mitsuhiko Yamada
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2010
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/1471-244X-10-30

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