Published in:
01-02-2004 | Poster presentation
Multicenter, randomized, double-blind trial comparing albumin and polygeline for intravascular fluid loading in patients with cirrhosis and tense ascites treated with paracentesis
Authors:
R Moreau, D Valla, D Golly, Z Tellier
Published in:
Critical Care
|
Special Issue 1/2004
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Excerpt
Patients with cirrhosis and tense ascites treated with paracentesis require repeated intravascular fluid loading with colloid solutions. In such patients, human albumin was suggested to be superior to a synthetic colloid for fluid loading, albeit at a higher cost. Thus, we started a 6-month trial aimed to compare the outcomes in patients with cirrhosis who were treated with albumin with the outcomes in those treated with bovine-derived polygeline. We also aimed to investigate hospital costs. This trial had to be prematurely interrupted due to theoretical concern regarding safety of bovine-derived products. …