Skip to main content
Top
Published in: International Journal of Emergency Medicine 1/2015

Open Access 01-12-2015 | Case report

Multi-organ dysfunction secondary to severe wasp envenomation

Authors: Abraham M Ittyachen, Shanavas Abdulla, Rifzana Fathima Anwarsha, Bhavya S Kumar

Published in: International Journal of Emergency Medicine | Issue 1/2015

Login to get access

Abstract

Wasp sting is not an uncommon incident. Around 56% to 94% of the population is stung at least once in their lifetime by a member of the order Hymenoptera which includes wasps, bees, and ants. The response to a wasp sting may vary from mild local reaction to severe systemic and anaphylactic reactions. The clinical picture and mortality rate tend to be more severe in adults compared to children. We present a 32-year-old agricultural worker who was bitten by multiple wasps while on a coconut tree. In spite of the heavy load of venom due to the multiple bites, the patient did not develop anaphylaxis. However, a delayed reaction did occur within 48 h in the form of severe multi-organ dysfunction. There was significant improvement by around 2 weeks; but it took another 6 months for the serum creatinine to normalize. This case highlights the occupational risk of Hymenoptera envenomation, the life-threatening complications that may follow and which may even be delayed as was the case with this patient, and the value of emergency care and intensive management which can result in a favorable clinical outcome.
Literature
1.
go back to reference Antonicelli L, Bilo MB, Bonifazi F. Epidemiology of Hymenoptera allergy. Curr Opin Allergy Clin Immunol. 2002;2:341–6.CrossRefPubMed Antonicelli L, Bilo MB, Bonifazi F. Epidemiology of Hymenoptera allergy. Curr Opin Allergy Clin Immunol. 2002;2:341–6.CrossRefPubMed
2.
go back to reference Biló BM, Rueff F, Mosbech H, Bonifazi F, Oude-Elberink JN. Diagnosis of Hymenoptera venom allergy. Allergy. 2005;60(11):1339–49.CrossRefPubMed Biló BM, Rueff F, Mosbech H, Bonifazi F, Oude-Elberink JN. Diagnosis of Hymenoptera venom allergy. Allergy. 2005;60(11):1339–49.CrossRefPubMed
3.
go back to reference Mueller UR. Clinical presentation and pathogenesis. In: Mueller UR, editor. Insect sting allergy: clinical picture, diagnosis and treatment. Gustav Fischer Verlag: Stuttgart; 1990. p. 33–65. Mueller UR. Clinical presentation and pathogenesis. In: Mueller UR, editor. Insect sting allergy: clinical picture, diagnosis and treatment. Gustav Fischer Verlag: Stuttgart; 1990. p. 33–65.
4.
go back to reference Lockey RF, Turkeltaub PC, Baird-Warren IA, Olive CA, Olive ES, Peppe BC, et al. The Hymenoptera venom study I, 1979–1982: demographics and history-sting data. J Allergy Clin Immunol. 1988;82:370–81.CrossRefPubMed Lockey RF, Turkeltaub PC, Baird-Warren IA, Olive CA, Olive ES, Peppe BC, et al. The Hymenoptera venom study I, 1979–1982: demographics and history-sting data. J Allergy Clin Immunol. 1988;82:370–81.CrossRefPubMed
5.
go back to reference Lantner R, Reisman RE. Clinical and immunologic features and subsequent course of patients with severe insect sting anaphylaxis. J Allergy Clin Immunol. 1989;84:900–6.CrossRef Lantner R, Reisman RE. Clinical and immunologic features and subsequent course of patients with severe insect sting anaphylaxis. J Allergy Clin Immunol. 1989;84:900–6.CrossRef
6.
go back to reference Annila IT, Karjalainen ES, Annila PA, Kuusisto PA. Bee and wasp sting reactions in current beekeepers. Ann Allergy Asthma Immunol. 1996;77:423–7.CrossRefPubMed Annila IT, Karjalainen ES, Annila PA, Kuusisto PA. Bee and wasp sting reactions in current beekeepers. Ann Allergy Asthma Immunol. 1996;77:423–7.CrossRefPubMed
7.
go back to reference Pucci S, Antonicelli L, Bilo MB, Garritani MS, Bonifazi F. Shortness of interval between two stings as risk factor for developing Hymenoptera venom allergy. Allergy. 1994;49:894–6.CrossRef Pucci S, Antonicelli L, Bilo MB, Garritani MS, Bonifazi F. Shortness of interval between two stings as risk factor for developing Hymenoptera venom allergy. Allergy. 1994;49:894–6.CrossRef
8.
go back to reference Muller UR. Bee venom allergy in beekeepers and their family members. Curr Opin Allergy Clin Immunol. 2005;5:343–7.CrossRefPubMed Muller UR. Bee venom allergy in beekeepers and their family members. Curr Opin Allergy Clin Immunol. 2005;5:343–7.CrossRefPubMed
9.
go back to reference Hoffman DR, Jacobson RS. Allergens in Hymenoptera venom: XII how much protein is in a sting? Ann Allergy. 1984;52:276–8.PubMed Hoffman DR, Jacobson RS. Allergens in Hymenoptera venom: XII how much protein is in a sting? Ann Allergy. 1984;52:276–8.PubMed
10.
go back to reference King TP, Kochoumian L, Joslyn A. Wasp venom proteins: phospholipase A1 and B. Arch Biochem Biophys. 1984;230:1–12.CrossRefPubMed King TP, Kochoumian L, Joslyn A. Wasp venom proteins: phospholipase A1 and B. Arch Biochem Biophys. 1984;230:1–12.CrossRefPubMed
11.
go back to reference Vikrant S, Pandey D, Machhan P, Gupta D, Kaushal SS, Grover N. Wasp envenomation-induced acute renal failure: a report of three cases. Nephrology (Carlton). 2005;10(6):548–52.CrossRef Vikrant S, Pandey D, Machhan P, Gupta D, Kaushal SS, Grover N. Wasp envenomation-induced acute renal failure: a report of three cases. Nephrology (Carlton). 2005;10(6):548–52.CrossRef
12.
go back to reference Chao YW, Yang AH, Ng YY, Yang WC. Acute interstitial nephritis and pigmented tubulopathy in a patient after wasp stings. Am J Kidney Dis. 2004;43(2):e15–9.CrossRef Chao YW, Yang AH, Ng YY, Yang WC. Acute interstitial nephritis and pigmented tubulopathy in a patient after wasp stings. Am J Kidney Dis. 2004;43(2):e15–9.CrossRef
13.
go back to reference Wagdi P, Mehan VK, Bürgi H, Salzmann C. Acute myocardial infarction after wasp stings in a patient with normal coronary arteries. Am Heart J. 1994;128(4):820–3.CrossRefPubMed Wagdi P, Mehan VK, Bürgi H, Salzmann C. Acute myocardial infarction after wasp stings in a patient with normal coronary arteries. Am Heart J. 1994;128(4):820–3.CrossRefPubMed
14.
go back to reference Rowe SF, Greer KE, Hodge Jr RH. Electrocardiographic changes associated with multiple yellow jacket stings. South Med J. 1979;72(4):483–5.CrossRefPubMed Rowe SF, Greer KE, Hodge Jr RH. Electrocardiographic changes associated with multiple yellow jacket stings. South Med J. 1979;72(4):483–5.CrossRefPubMed
15.
go back to reference Tsai CL, Fang CC, Chen WJ, Dierberg K. Hornet sting-induced toxic hepatitis. Clin Toxicol (Phila). 2005;43(2):127–8.CrossRef Tsai CL, Fang CC, Chen WJ, Dierberg K. Hornet sting-induced toxic hepatitis. Clin Toxicol (Phila). 2005;43(2):127–8.CrossRef
16.
go back to reference Watemberg N, Weizman Z, Shahak E, Aviram M, Maor E. Fatal multiple organ failure following massive hornet stings. J Toxicol Clin Toxicol. 1995;33(5):471–4.CrossRefPubMed Watemberg N, Weizman Z, Shahak E, Aviram M, Maor E. Fatal multiple organ failure following massive hornet stings. J Toxicol Clin Toxicol. 1995;33(5):471–4.CrossRefPubMed
17.
go back to reference Volders J, Smits M, Folkersma G, Tjan DH. An unusual neurological consequence of massive wasp stings. BMJ Case Rep. 2012;28:2012. doi:10.1136/bcr.01.2012.5555. Volders J, Smits M, Folkersma G, Tjan DH. An unusual neurological consequence of massive wasp stings. BMJ Case Rep. 2012;28:2012. doi:10.1136/bcr.01.2012.5555.
18.
go back to reference Sachdev A, Mahapatra M, D’Cruz S, Kumar A, Singh R, Lehl SS. Wasp sting induced neurological manifestations. Neurol India. 2002;50(3):319–21.PubMed Sachdev A, Mahapatra M, D’Cruz S, Kumar A, Singh R, Lehl SS. Wasp sting induced neurological manifestations. Neurol India. 2002;50(3):319–21.PubMed
19.
go back to reference Lombardini C, Helia RE, Boehlen F, Merlani P. “Heparinization” and hyperfibrinogenolysis by wasp sting. Am J Emerg Med. 2009;27(9):1176.e1–3. doi:10.1016/j.ajem.2009.02.005.CrossRef Lombardini C, Helia RE, Boehlen F, Merlani P. “Heparinization” and hyperfibrinogenolysis by wasp sting. Am J Emerg Med. 2009;27(9):1176.e1–3. doi:10.1016/j.ajem.2009.02.005.CrossRef
20.
21.
go back to reference Krishna MT, Ewan PW, Diwalar L, Durham SR, Frew AJ, Leech SC, et al. British Society for Allergy and Clinical Immunology: Diagnosis and management of hymenoptera venom allergy: British Society for Allergy and Clinical Immunology (BSACI) guidelines. Clin Exp Allergy. 2011;41(9):1201–20. doi:10.1111/j.1365-2222.2011.03788.x.CrossRefPubMed Krishna MT, Ewan PW, Diwalar L, Durham SR, Frew AJ, Leech SC, et al. British Society for Allergy and Clinical Immunology: Diagnosis and management of hymenoptera venom allergy: British Society for Allergy and Clinical Immunology (BSACI) guidelines. Clin Exp Allergy. 2011;41(9):1201–20. doi:10.1111/j.1365-2222.2011.03788.x.CrossRefPubMed
22.
go back to reference Schoen EJ. Temporal arteritis after Hymenoptera sting. J Rheumatol. 1998;25(10):2040–2.PubMed Schoen EJ. Temporal arteritis after Hymenoptera sting. J Rheumatol. 1998;25(10):2040–2.PubMed
23.
go back to reference Ruëff F, Przybilla B, Biló MB, Müller U, Scheipl F, Seitz MJ, et al. Clinical effectiveness of hymenoptera venom immunotherapy: a prospective observational multicenter study of the European Academy of Allergology and Clinical Immunology Interest Group on Insect Venom Hypersensitivity. PLoS One. 2013;8(5):e63233. doi:10.1371/journal.pone.0063233.CrossRefPubMedCentralPubMed Ruëff F, Przybilla B, Biló MB, Müller U, Scheipl F, Seitz MJ, et al. Clinical effectiveness of hymenoptera venom immunotherapy: a prospective observational multicenter study of the European Academy of Allergology and Clinical Immunology Interest Group on Insect Venom Hypersensitivity. PLoS One. 2013;8(5):e63233. doi:10.1371/journal.pone.0063233.CrossRefPubMedCentralPubMed
24.
go back to reference Palgan K, Bartuzi Z, Gotz-Zbikowska M. Treatment with a combination of omalizumab and specific immunotherapy for severe anaphylaxis after a wasp sting. Int J Immunopathol Pharmacol. 2014;27(1):109–12.PubMed Palgan K, Bartuzi Z, Gotz-Zbikowska M. Treatment with a combination of omalizumab and specific immunotherapy for severe anaphylaxis after a wasp sting. Int J Immunopathol Pharmacol. 2014;27(1):109–12.PubMed
Metadata
Title
Multi-organ dysfunction secondary to severe wasp envenomation
Authors
Abraham M Ittyachen
Shanavas Abdulla
Rifzana Fathima Anwarsha
Bhavya S Kumar
Publication date
01-12-2015
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Emergency Medicine / Issue 1/2015
Print ISSN: 1865-1372
Electronic ISSN: 1865-1380
DOI
https://doi.org/10.1186/s12245-015-0054-7

Other articles of this Issue 1/2015

International Journal of Emergency Medicine 1/2015 Go to the issue

State of International Emergency Medicine

State of emergency medicine in Colombia