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Translational Stroke Research
Published in: Translational Stroke Research 1/2012

01-03-2012 | Review Article

MRI Stem Cell Tracking for Therapy in Experimental Cerebral Ischemia

Authors: Pedro Ramos-Cabrer, Mathias Hoehn

Published in: Translational Stroke Research | Issue 1/2012

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Abstract

Magnetic resonance has an established role in investigations on the evolution of stroke and the assessment of therapeutic strategies in experimental animals. Here we show that the technique has also an important place for the study of stem cell-mediated regenerative therapies after stroke. We review the literature by bridging from the methodological aspects of stem cell labeling via grafting and monitoring of cell dynamics after implantation into the brain all the way to MRI's role in analyzing the stem cell-mediated functional improvement. Thus, we have aimed at a view combining the focus on the monitoring of the cell activities with the aspect of lesion evolution while including also the essence of a potential functional improvement by the implantation of stem cells following stroke.
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Metadata
Title
MRI Stem Cell Tracking for Therapy in Experimental Cerebral Ischemia
Authors
Pedro Ramos-Cabrer
Mathias Hoehn
Publication date
01-03-2012
Publisher
Springer-Verlag
Published in
Translational Stroke Research / Issue 1/2012
Print ISSN: 1868-4483
Electronic ISSN: 1868-601X
DOI
https://doi.org/10.1007/s12975-011-0111-3

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