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Open Access 01-12-2010 | Commentary

MRI plaque imaging and its role in population-based studies

Authors: Chun Yuan, Jarett D Berry

Published in: BMC Medicine | Issue 1/2010

Abstract

Noninvasive direct vessel wall (plaque) imaging may provide a good opportunity to study unique aspects of atherosclerotic lesions in different populations. The article published by Esposito et al. provides new insights into our understanding of diabetic atherosclerotic vascular disease by using direct plaque imaging techniques. The findings from this article call for attention to more in vivo imaging to understand the nature of high-risk atherosclerosis, especially in prospective studies in diabetic patients.

See research article: http://www.biomedcentral.com/1471-2342/10/27/abstract

Esposito L, Saam T, Heider P, Bockelbrink A, Pelisek J, Sepp D, Feuer R, Winkler C, Liebig T, Holzer K, Pauly O, Sadikovic S, Hemmer B, Poppert H: MRI plaque imaging reveals high-risk carotid plaques especially in diabetic patients irrespective of the degree of stenosis. BMC Med Imaging. 2010, 10: 27-10.1186/1471-2342-10-27.CrossRefPubMedPubMedCentral

Meijer WT, Hoes AW, Rutgers D, Bots ML, Hofman A, Grobbee DE: Peripheral arterial disease in the elderly: The Rotterdam Study. Arterioscler Thromb Vasc Biol. 1998, 18: 185-192.CrossRefPubMed

Beckman JA, Creager MA, Libby P: Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA. 2002, 287: 2570-2581. 10.1001/jama.287.19.2570.CrossRefPubMed

Hiatt WR, Hoag S, Hamman RF: Effect of diagnostic criteria on the prevalence of peripheral arterial disease: the San Luis Valley Diabetes Study. Circulation. 1995, 91: 1472-1479.CrossRefPubMed

Fabris F, Zanocchi M, Bo M, Fonte G, Poli L, Bergoglio I, Ferrario E, Pernigotti L: Carotid plaque, aging, and risk factors: a study of 457 subjects. Stroke. 1994, 25: 1133-1140.CrossRefPubMed

Yuan C, Kerwin WS, Yarnykh VL, Cai J, Saam T, Chu B, Takaya N, Ferguson MS, Underhill H, Xu D, Liu F, Hatsukami TS: MRI of atherosclerosis in clinical trials. NMR Biomed. 2006, 19: 636-654. 10.1002/nbm.1065.CrossRefPubMed

Cai JM, Hatsukami TS, Ferguson MS, Small R, Polissar NL, Yuan C: Classification of human carotid atherosclerotic lesions with in vivo multicontrast magnetic resonance imaging. Circulation. 2002, 106: 1368-1373. 10.1161/01.CIR.0000028591.44554.F9.CrossRefPubMed

Cai J, Hatsukami TS, Ferguson MS, Kerwin WS, Saam T, Chu B, Takaya N, Polissar NL, Yuan C: In vivo quantitative measurement of intact fibrous cap and lipid-rich necrotic core size in atherosclerotic carotid plaque: comparison of high-resolution, contrast-enhanced magnetic resonance imaging and histology. Circulation. 2005, 112: 3437-3444. 10.1161/CIRCULATIONAHA.104.528174.CrossRefPubMed

Saam T, Ferguson MS, Yarnykh VL, Takaya N, Xu D, Polissar NL, Hatsukami TS, Yuan C: Quantitative evaluation of carotid plaque composition by in vivo MRI. Arterioscler Thromb Vasc Biol. 2005, 25: 234-239. 10.1161/01.ATV.0000155965.54679.79.CrossRefPubMed

10.

Takaya N, Yuan C, Chu B, Saam T, Underhill H, Cai J, Tran N, Polissar NL, Isaac C, Ferguson MS, Garden GA, Cramer SC, Maravilla KR, Hashimoto B, Hatsukami TS: Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospective assessment with MRI: initial results. Stroke. 2006, 37: 818-823. 10.1161/01.STR.0000204638.91099.91.CrossRefPubMed

11.

Takaya N, Yuan C, Chu B, Saam T, Polissar NL, Jarvik GP, Isaac C, McDonough J, Natiello C, Small R, Ferguson MS, Hatsukami TS: Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques: a high-resolution magnetic resonance imaging study. Circulation. 2005, 111: 2768-2775. 10.1161/CIRCULATIONAHA.104.504167.CrossRefPubMed

12.

Luscher TF, Creager MA, Beckman JA, Cosentino F: Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part II. Circulation. 2003, 108: 1655-1661. 10.1161/01.CIR.0000089189.70578.E2.CrossRefPubMed

13.

Creager MA, Luscher TF, Cosentino F, Beckman JA: Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I. Circulation. 2003, 108: 1527-1532. 10.1161/01.CIR.0000091257.27563.32.CrossRefPubMed

14.

Cipollone F, Iezzi A, Fazia M, Zucchelli M, Pini B, Cuccurullo C, De Cesare D, De Blasis G, Muraro R, Bei R, Chiarelli F, Schmidt AM, Cuccurullo F, Mezzetti A: The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic control. Circulation. 2003, 108: 1070-1077. 10.1161/01.CIR.0000086014.80477.0D.CrossRefPubMed

15.

Cosentino F, Hishikawa K, Katusic ZS, Luscher TF: High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation. 1997, 96: 25-28.CrossRefPubMed

16.

Luscher TF, Steffel J: Sweet and sour: unraveling diabetic vascular disease. Circ Res. 2008, 102: 9-11. 10.1161/01.RES.0000303937.73170.31.CrossRefPubMed

17.

Burke AP, Kolodgie FD, Zieske A, Fowler DR, Weber DK, Varghese PJ, Farb A, Virmani R: Morphologic findings of coronary atherosclerotic plaques in diabetics: a postmortem study. Arterioscler Thromb Vasc Biol. 2004, 24: 1266-1271. 10.1161/01.ATV.0000131783.74034.97.CrossRefPubMed

18.

Wasserman BA, Sharrett AR, Lai S, Gomes AS, Cushman M, Folsom AR, Bild DE, Kronmal RA, Sinha S, Bluemke DA: Risk factor associations with the presence of a lipid core in carotid plaque of asymptomatic individuals using high-resolution MRI: the multi-ethnic study of atherosclerosis (MESA). Stroke. 2008, 39: 329-335. 10.1161/STROKEAHA.107.498634.CrossRefPubMed

19.

Wagenknecht L, Wasserman B, Chambless L, Coresh J, Folsom A, Mosley T, Ballantyne C, Sharrett R, Boerwinkle E: Correlates of carotid plaque presence and composition as measured by MRI: the Atherosclerosis Risk in Communities Study. Circ Cardiovasc Imaging. 2009, 2: 314-322. 10.1161/CIRCIMAGING.108.823922.CrossRefPubMedPubMedCentral

20.

Underhill HR, Yuan C, Yarnykh VL, Chu B, Oikawa M, Dong L, Polissar NL, Garden GA, Cramer SC, Hatsukami TS: Predictors of surface disruption with MR imaging in asymptomatic carotid artery stenosis. AJNR Am J Neuroradiol. 2010, 31: 487-493. 10.3174/ajnr.A1842.CrossRefPubMed

21.

Balu N, Chu B, Hatsukami TS, Yuan C, Yarnykh VL: Comparison between 2D and 3D high-resolution black-blood techniques for carotid artery wall imaging in clinically significant atherosclerosis. J Magn Reson Imaging. 2008, 27: 918-924. 10.1002/jmri.21282.CrossRefPubMedPubMedCentral

The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1741-7015/8/78/prepub

Title: MRI plaque imaging and its role in population-based studies
Authors: Chun Yuan
Jarett D Berry
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: BMC Medicine / Issue 1/2010
Electronic ISSN: 1741-7015
DOI: https://doi.org/10.1186/1741-7015-8-78

Keynote webinar | Spotlight on medication adherence

Springer Medicine

MRI plaque imaging and its role in population-based studies

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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