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Open Access 01-08-2012 | Guideline

MRI of the lung (1/3): methods

Authors: J. M. Wild, H. Marshall, M. Bock, L. R. Schad, P. M. Jakob, M. Puderbach, F. Molinari, E. J. R. Van Beek, J. Biederer

Published in: Insights into Imaging | Issue 4/2012

Abstract

Proton magnetic resonance imaging (MRI) has recently emerged as a clinical tool to image the lungs. This paper outlines the current technical aspects of MRI pulse sequences, radiofrequency (RF) coils and MRI system requirements needed for imaging the pulmonary parenchyma and vasculature. Lung MRI techniques are presented as a “technical toolkit”, from which MR protocols will be composed in the subsequent papers for comprehensive imaging of lung disease and function (parts 2 and 3). This paper is pitched at MR scientists, technicians and radiologists who are interested in understanding and establishing lung MRI methods. Images from a 1.5 T scanner are used for illustration of the sequences and methods that are highlighted.

Main Messages

• Outline of the hardware and pulse sequence requirements for proton lung MRI

• Overview of pulse sequences for lung parenchyma, vascular and functional imaging with protons

• Demonstration of the pulse-sequence building blocks for clinical lung MRI protocols

Biederer J, Beer M, Hirsch W, Wild J, Fabel M, Puderbach M et al (2012) MRI of the lung (2/3). Why… when… how? Insights Imaging, epub Feb 13; doi:10.1007/s13244-011-0146-8

Biederer J, Mirsadraee S, Beer M, Molinari F, Hintze C, Bauman G et al (2012) MRI of the lung (3/3)—current applications and future perspectives. Insights Imaging. doi:10.1007/s13244-011-0142-z

Muller CJ, Loffler R, Deimling M, Peller M, Reiser M (2001) MR lung imaging at 0.2 T with T1-weighted true FISP: native and oxygen-enhanced. J Magn Reson Imaging 14(2):164–168CrossRefPubMed

Anjorin A, Schmidt H, Posselt HG, Smaczny C, Ackermann H, Deimling M et al (2008) Comparative evaluation of chest radiography, low-field MRI, the Shwachman-Kulczycki score and pulmonary function tests in patients with cystic fibrosis. Eur Radiol 18(6):1153–1161CrossRefPubMed

Arnold JF, Morchel P, Glaser E, Pracht ED, Jakob PM (2007) Lung MRI using an MR-compatible active breathing control (MR-ABC). Magn Reson Med 58(6):1092–1098CrossRefPubMed

Oechsner M, Pracht ED, Staeb D, Arnold JF, Kostler H, Hahn D et al (2009) Lung imaging under free-breathing conditions. Magn Reson Med 61(3):723–727CrossRefPubMed

Schulz J, Korn M, Deimling M, Semmler W, Bock M (2008) Flow-compensated self-gating. Magma 21(5):307–315CrossRefPubMed

Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P (1999) SENSE: sensitivity encoding for fast MRI. Magn Reson Med 42(5):952–962CrossRefPubMed

Puderbach M, Hintze C, Ley S, Eichinger M, Kauczor HU, Biederer J (2007) MR imaging of the chest: a practical approach at 1.5T. Eur J Radiol 64(3):345–355CrossRefPubMed

10.

Swift AJ, Woodhouse N, Fichele S, Siedel J, Mills GH, van Beek EJ et al (2007) Rapid lung volumetry using ultrafast dynamic magnetic resonance imaging during forced vital capacity maneuver: correlation with spirometry. Invest Radiol 42(1):37–41CrossRefPubMed

11.

Biederer J, Hintze C, Fabel M, Dinkel J (2010) Magnetic resonance imaging and computed tomography of respiratory mechanics. J Magn Reson Imaging 32(6):1388–1397CrossRefPubMed

12.

Rajaram S, Swift AJ, Capener D, Telfer A, Davies C, Hill C et al (2012) Lung morphology assessment with balanced steady-state free precession MR imaging compared with CT. Radiology 6:6

13.

Huang TY, Huang IJ, Chen CY, Scheffler K, Chung HW, Cheng HC (2002) Are TrueFISP images T2/T1-weighted? Magn Reson Med 48(4):684–688CrossRefPubMed

14.

Hui BK, Noga ML, Gan KD, Wilman AH (2005) Navigator-gated three-dimensional MR angiography of the pulmonary arteries using steady-state free precession. J Magn Reson Imaging 21(6):831–835CrossRefPubMed

15.

Hennig J, Nauerth A, Friedburg H (1986) RARE imaging: a fast imaging method for clinical MR. Magn Reson Med 3(6):823–833CrossRefPubMed

16.

Griswold MA, Blaimer M, Breuer F, Heidemann RM, Mueller M, Jakob PM (2005) Parallel magnetic resonance imaging using the GRAPPA operator formalism. Magn Reson Med 54(6):1553–1556CrossRefPubMed

17.

Heidemann RM, Griswold MA, Kiefer B, Nittka M, Wang J, Jellus V et al (2003) Resolution enhancement in lung 1H imaging using parallel imaging methods. Magn Reson Med 49(2):391–394CrossRefPubMed

18.

Henzler T, Dietrich O, Krissak R, Wichmann T, Lanz T, Reiser MF et al (2009) Half-Fourier-acquisition single-shot turbo spin-echo (HASTE) MRI of the lung at 3 Tesla using parallel imaging with 32-receiver channel technology. J Magn Reson Imaging 30(3):541–546CrossRefPubMed

19.

Bergin CJ, Pauly JM, Macovski A (1991) Lung parenchyma: projection reconstruction MR imaging. Radiology 179(3):777–781CrossRefPubMed

20.

Leung DA, McKinnon GC, Davis CP, Pfammatter T, Krestin GP, Debatin JF (1996) Breath-hold, contrast-enhanced, three-dimensional MR angiography. Radiology 200(2):569–571CrossRefPubMed

21.

Fink C, Puderbach M, Bock M, Lodemann KP, Zuna I, Schmahl A et al (2004) Regional lung perfusion: assessment with partially parallel three-dimensional MR imaging. Radiology 231(1):175–184CrossRefPubMed

22.

Wilman AH, Riederer SJ (1997) Performance of an elliptical centric view order for signal enhancement and motion artifact suppression in breath-hold three-dimensional gradient echo imaging. Magn Reson Med 38(5):793–802CrossRefPubMed

23.

Korosec FR, Frayne R, Grist TM, Mistretta CA (1996) Time-resolved contrast-enhanced 3D MR angiography. Magn Reson Med 36(3):345–351CrossRefPubMed

24.

Puderbach M, Risse F, Biederer J, Ley-Zaporozhan J, Ley S, Szabo G et al (2008) In vivo Gd-DTPA concentration for MR lung perfusion measurements: assessment with computed tomography in a porcine model. Eur Radiol 18(10):2102–2107CrossRefPubMed

25.

Wang T, Schultz G, Hebestreit H, Hebestreit A, Hahn D, Jakob PM (2003) Quantitative perfusion mapping of the human lung using 1H spin labeling. J Magn Reson Imaging 18(2):260–265CrossRefPubMed

26.

Stadler A, Jakob PM, Griswold M, Barth M, Bankier AA (2005) T1 mapping of the entire lung parenchyma: influence of the respiratory phase in healthy individuals. J Magn Reson Imaging 21(6):759–764CrossRefPubMed

27.

Edelman RR, Hatabu H, Tadamura E, Li W, Prasad PV (1996) Noninvasive assessment of regional ventilation in the human lung using oxygen-enhanced magnetic resonance imaging. Nat Med 2(11):1236–1239CrossRefPubMed

28.

Jakob PM, Hillenbrand CM, Wang T, Schultz G, Hahn D, Haase A (2001) Rapid quantitative lung (1)H T(1) mapping. J Magn Reson Imaging 14(6):795–799CrossRefPubMed

29.

Jakob PM, Wang T, Schultz G, Hebestreit H, Hebestreit A, Hahn D (2004) Assessment of human pulmonary function using oxygen-enhanced T(1) imaging in patients with cystic fibrosis. Magn Reson Med 51(5):1009–1016CrossRefPubMed

30.

Molinari F, Puderbach M, Eichinger M, Ley S, Fink C, Bonomo L et al (2008) Oxygen-enhanced magnetic resonance imaging: influence of different gas delivery methods on the T1-changes of the lungs. Invest Radiol 43(6):427–432CrossRefPubMed

31.

J. V. Deimling M, Geiger B, Chefd’Hotel C (2008) Time resolved lung ventilation imaging by fourier decomposition. In: Proceedings of the 16th Annual Meeting of ISMRM, Toronto, Ontario, Canada

32.

Bauman G, Puderbach M, Deimling M, Jellus V, Chefd’hotel C, Dinkel J et al (2009) Non-contrast-enhanced perfusion and ventilation assessment of the human lung by means of fourier decomposition in proton MRI. Magn Reson Med 62(3):656–664CrossRefPubMed

Title: MRI of the lung (1/3): methods
Authors: J. M. Wild
H. Marshall
M. Bock
L. R. Schad
P. M. Jakob
M. Puderbach
F. Molinari
E. J. R. Van Beek
J. Biederer
Publication date: 01-08-2012
Publisher: Springer Berlin Heidelberg
Published in: Insights into Imaging / Issue 4/2012
Electronic ISSN: 1869-4101
DOI: https://doi.org/10.1007/s13244-012-0176-x

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