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Published in: European Radiology 11/2010

Open Access 01-11-2010 | Gastrointestinal

MRI for the evaluation of gastric physiology

Authors: Ingrid M. de Zwart, Albert de Roos

Published in: European Radiology | Issue 11/2010

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Abstract

Background:

Evaluation of gastric physiology (gastric emptying and motility) is important for the diagnosis of disturbances such as functional dyspepsia. MRI is a non-invasive technique that allows simultaneous registration of gastric emptying and motility.

Aim:

To provide an overview of the literature of studies that used MRI as a tool for evaluation of gastric function in both research and clinical settings.

Materials and methods:

A MEDLINE search was performed (1990–2008) directed at the radiology and gastroenterology literature on gastric physiology. Key words that were used included: functional tests, gastric emptying, gastric motility, gastric physiology and MRI. Twenty-five articles fulfilled the inclusion criteria and were included in the analysis.

Results and conclusion:

Over the last decade, MRI has developed as a reliable, non-invasive method for detailed evaluation of gastric emptying and motility without the disadvantages of ionizing radiation and without the use of intragastric catheters that influence gastric physiology.
Literature
1.
go back to reference Tack J, Piessevaux H, Coulie B, Caenepeel P, Janssens J (1998) Role of impaired gastric accommodation to a meal in functional dyspepsia. Gastroenterology 115:1346–1352CrossRefPubMed Tack J, Piessevaux H, Coulie B, Caenepeel P, Janssens J (1998) Role of impaired gastric accommodation to a meal in functional dyspepsia. Gastroenterology 115:1346–1352CrossRefPubMed
2.
go back to reference Vu MK, Straathof JWA, Van der Schaar PJ, Arndt JW, Ringers J, Lamers CBHW et al (1999) Motor and sensory function of the proximal stomach in reflux disease and after laparoscopic Nissen fundoplication. Am J Gastroenterol 94:1481–1489CrossRefPubMed Vu MK, Straathof JWA, Van der Schaar PJ, Arndt JW, Ringers J, Lamers CBHW et al (1999) Motor and sensory function of the proximal stomach in reflux disease and after laparoscopic Nissen fundoplication. Am J Gastroenterol 94:1481–1489CrossRefPubMed
3.
go back to reference Whitehead WE, Delvaux M (1997) Standardization of barostat procedures for testing smooth muscle tone and sensory thresholds in the gastrointestinal tract. The working team of Glaxo-Wellcome research, UK. Dig Dis Sci 42:223–241CrossRefPubMed Whitehead WE, Delvaux M (1997) Standardization of barostat procedures for testing smooth muscle tone and sensory thresholds in the gastrointestinal tract. The working team of Glaxo-Wellcome research, UK. Dig Dis Sci 42:223–241CrossRefPubMed
4.
go back to reference Kunz P, Crelier GR, Schwizer W, Borovicka J, Kreiss C, Fried M et al (1998) Gastric emptying and motility: assessment with MR imaging—preliminary observations [see comments]. Radiology 207:33–40PubMed Kunz P, Crelier GR, Schwizer W, Borovicka J, Kreiss C, Fried M et al (1998) Gastric emptying and motility: assessment with MR imaging—preliminary observations [see comments]. Radiology 207:33–40PubMed
5.
go back to reference Kunz P, Feinle C, Schwizer W, Fried M, Boesiger P (1999) Assessment of gastric motor function during the emptying of solid and liquid meals in humans by MRI. J Magn Reson Imaging 9:75–80CrossRefPubMed Kunz P, Feinle C, Schwizer W, Fried M, Boesiger P (1999) Assessment of gastric motor function during the emptying of solid and liquid meals in humans by MRI. J Magn Reson Imaging 9:75–80CrossRefPubMed
6.
go back to reference Boulby P, Moore R, Gowland P, Spiller RC (1999) Fat delays emptying but increases forward and backward antral flow as assessed by flow-sensitive magnetic resonance imaging. Neurogastroenterol Motil 11:27–36CrossRefPubMed Boulby P, Moore R, Gowland P, Spiller RC (1999) Fat delays emptying but increases forward and backward antral flow as assessed by flow-sensitive magnetic resonance imaging. Neurogastroenterol Motil 11:27–36CrossRefPubMed
7.
go back to reference Wright J, Evans D, Gowland P, Mansfield P (1999) Validation of antroduodenal motility measurements made by echo-planar magnetic resonance imaging. Neurogastroenterol Motil 11:19–25CrossRefPubMed Wright J, Evans D, Gowland P, Mansfield P (1999) Validation of antroduodenal motility measurements made by echo-planar magnetic resonance imaging. Neurogastroenterol Motil 11:19–25CrossRefPubMed
8.
go back to reference Feinle C, Kunz P, Boesiger P, Fried M, Schwizer W (1999) Scintigraphic validation of a magnetic resonance imaging method to study gastric emptying of a solid meal in humans. Gut 44:106–111CrossRefPubMed Feinle C, Kunz P, Boesiger P, Fried M, Schwizer W (1999) Scintigraphic validation of a magnetic resonance imaging method to study gastric emptying of a solid meal in humans. Gut 44:106–111CrossRefPubMed
9.
go back to reference Ajaj W, Goehde SC, Papanikolaou N, Holtmann G, Ruehm SG, Debatin JF et al (2004) Real time high resolution magnetic resonance imaging for the assessment of gastric motility disorders. Gut 53:1256–1261CrossRefPubMed Ajaj W, Goehde SC, Papanikolaou N, Holtmann G, Ruehm SG, Debatin JF et al (2004) Real time high resolution magnetic resonance imaging for the assessment of gastric motility disorders. Gut 53:1256–1261CrossRefPubMed
10.
go back to reference Borovicka J, Lehmann R, Kunz P, Fraser R, Kreiss C, Crelier G et al (1999) Evaluation of gastric emptying and motility in diabetic gastroparesis with magnetic resonance imaging: effects of cisapride. Am J Gastroenterol 94:2866–2873CrossRefPubMed Borovicka J, Lehmann R, Kunz P, Fraser R, Kreiss C, Crelier G et al (1999) Evaluation of gastric emptying and motility in diabetic gastroparesis with magnetic resonance imaging: effects of cisapride. Am J Gastroenterol 94:2866–2873CrossRefPubMed
11.
go back to reference Fruehauf H, Goetze O, Steingoetter A, Kwiatek M, Boesiger P, Thumshirn M et al (2007) Intersubject and intrasubject variability of gastric volumes in response to isocaloric liquid meals in functional dyspepsia and health. Neurogastroenterol Motil 19:553–561CrossRefPubMed Fruehauf H, Goetze O, Steingoetter A, Kwiatek M, Boesiger P, Thumshirn M et al (2007) Intersubject and intrasubject variability of gastric volumes in response to isocaloric liquid meals in functional dyspepsia and health. Neurogastroenterol Motil 19:553–561CrossRefPubMed
12.
go back to reference Richter J (1991) Dyspepsia: organic causes and differential characteristics from functional dyspepsia. Scand J Gastroenterol Suppl 182:11–16CrossRefPubMed Richter J (1991) Dyspepsia: organic causes and differential characteristics from functional dyspepsia. Scand J Gastroenterol Suppl 182:11–16CrossRefPubMed
13.
go back to reference Tack J, Broeckaert D, Coulie B, Janssens J (1998) The influence of cisapride on gastric tone and the perception of gastric distension. Aliment Pharmacol Ther 12:761–766CrossRefPubMed Tack J, Broeckaert D, Coulie B, Janssens J (1998) The influence of cisapride on gastric tone and the perception of gastric distension. Aliment Pharmacol Ther 12:761–766CrossRefPubMed
14.
go back to reference Schwizer W, Fraser R, Maecke H, Siebold K, Funck R, Fried M (1994) Gd-DOTA as a gastrointestinal contrast agent for gastric emptying measurements with MRI. Magn Reson Med 31:388–393CrossRefPubMed Schwizer W, Fraser R, Maecke H, Siebold K, Funck R, Fried M (1994) Gd-DOTA as a gastrointestinal contrast agent for gastric emptying measurements with MRI. Magn Reson Med 31:388–393CrossRefPubMed
15.
go back to reference de Zwart IM, Mearadji B, Lamb HJ, Eilers PHC, Masclee AAM, de Roos A et al (2002) Gastric motility: comparison of assessment with real-time MR imaging or barostat measurement—initial experience. Radiology 224:592–597CrossRefPubMed de Zwart IM, Mearadji B, Lamb HJ, Eilers PHC, Masclee AAM, de Roos A et al (2002) Gastric motility: comparison of assessment with real-time MR imaging or barostat measurement—initial experience. Radiology 224:592–597CrossRefPubMed
16.
go back to reference Kunz P, Feinle-Bisset C, Faas H, Boesiger P, Fried M, Steingoetter A et al (2005) Effect of ingestion order of the fat component of a solid meal on intragastric fat distribution and gastric emptying assessed by MRI. J Magn Reson Imaging 21:383–390CrossRefPubMed Kunz P, Feinle-Bisset C, Faas H, Boesiger P, Fried M, Steingoetter A et al (2005) Effect of ingestion order of the fat component of a solid meal on intragastric fat distribution and gastric emptying assessed by MRI. J Magn Reson Imaging 21:383–390CrossRefPubMed
17.
go back to reference Lauenstein TC, Vogt FM, Herborn CU, DeGreiff A, Debatin JF, Holtmann G (2003) Time-resolved three-dimensional MR imaging of gastric emptying modified by IV administration of erythromycin. Am J Roentgenol 180:1305–1310 Lauenstein TC, Vogt FM, Herborn CU, DeGreiff A, Debatin JF, Holtmann G (2003) Time-resolved three-dimensional MR imaging of gastric emptying modified by IV administration of erythromycin. Am J Roentgenol 180:1305–1310
18.
go back to reference Treier R, Steingoetter A, Weishaupt D, Goetze O, Boesiger P, Fried M et al (2006) Gastric motor function and emptying in the right decubitus and seated body position as assessed by magnetic resonance imaging. J Magn Reson Imaging 23:331–338CrossRefPubMed Treier R, Steingoetter A, Weishaupt D, Goetze O, Boesiger P, Fried M et al (2006) Gastric motor function and emptying in the right decubitus and seated body position as assessed by magnetic resonance imaging. J Magn Reson Imaging 23:331–338CrossRefPubMed
19.
go back to reference Schwizer W, Fraser R, Borovicka J, Asal K, Crelier G, Kunz P et al (1996) Measurement of proximal and distal gastric motility with magnetic resonance imaging. Am J Physiol 271(1 Pt 1):G217–G222PubMed Schwizer W, Fraser R, Borovicka J, Asal K, Crelier G, Kunz P et al (1996) Measurement of proximal and distal gastric motility with magnetic resonance imaging. Am J Physiol 271(1 Pt 1):G217–G222PubMed
20.
go back to reference Bilecen D, Scheffler K, Seifritz E, Bongartz G, Steinbrich W (2000) Hydro-MRI for the visualization of gastric wall motility using RARE magnetic resonance imaging sequences. Abdom Imaging 25:30–34CrossRefPubMed Bilecen D, Scheffler K, Seifritz E, Bongartz G, Steinbrich W (2000) Hydro-MRI for the visualization of gastric wall motility using RARE magnetic resonance imaging sequences. Abdom Imaging 25:30–34CrossRefPubMed
21.
go back to reference van der Geest RJ, Reiber JH (1999) Quantification in cardiac MRI. J Magn Reson Imaging 10:602–608CrossRefPubMed van der Geest RJ, Reiber JH (1999) Quantification in cardiac MRI. J Magn Reson Imaging 10:602–608CrossRefPubMed
22.
go back to reference Ajaj W, Lauenstein T, Papanikolaou N, Holtmann G, Goehde SC, Ruehm SG et al (2004) Real-time high-resolution MRI for the assessment of gastric motility: pre- and postpharmacological stimuli. J Magn Reson Imaging 19:453–458CrossRefPubMed Ajaj W, Lauenstein T, Papanikolaou N, Holtmann G, Goehde SC, Ruehm SG et al (2004) Real-time high-resolution MRI for the assessment of gastric motility: pre- and postpharmacological stimuli. J Magn Reson Imaging 19:453–458CrossRefPubMed
23.
go back to reference de Zwart IM, Haans JJ, Verbeek P, Eilers PH, de Roos A, Masclee AA (2007) Gastric accomodation and motility are influenced by the barostat device: assessment with magnetic resonance imaging. Am J Physiol Gastrointest Liver Physiol 292:G208–G214CrossRefPubMed de Zwart IM, Haans JJ, Verbeek P, Eilers PH, de Roos A, Masclee AA (2007) Gastric accomodation and motility are influenced by the barostat device: assessment with magnetic resonance imaging. Am J Physiol Gastrointest Liver Physiol 292:G208–G214CrossRefPubMed
24.
go back to reference Lee KJ, Kim JH, Cho SW (2006) Dietary influence on electro-gastrography and association of alterations in gastric myoelectrical activity with symptoms in patients with functional dyspepsia. J Gastroenterol Hepatol 21(1 Pt 1):59–64CrossRefPubMed Lee KJ, Kim JH, Cho SW (2006) Dietary influence on electro-gastrography and association of alterations in gastric myoelectrical activity with symptoms in patients with functional dyspepsia. J Gastroenterol Hepatol 21(1 Pt 1):59–64CrossRefPubMed
Metadata
Title
MRI for the evaluation of gastric physiology
Authors
Ingrid M. de Zwart
Albert de Roos
Publication date
01-11-2010
Publisher
Springer-Verlag
Published in
European Radiology / Issue 11/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-010-1850-3

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