A 19-year-old female presented at the twentieth day postpartum with severe headache, nausea and vomiting. She had no history of hypertension. Ambulatory blood pressure measurement values were normal. Proteinuria was not detected. In blood analysis, D-dimer level was normal. In addition, MR venography for sinus vein thrombosis was normal. However, MR imaging of the brain showed a lesion measuring approximately 1.5 cm in diameter in the splenium of the corpus callosum (SCC) (Fig. 1a–c). The lesion was hyperintense on the T2A sequences and showed limitation of diffusion on the diffusion-weighted sequences. Although the patient’s complaints regressed within 1 week, there were no changes in the MRI findings at that time. The lesion was found to be completely healed on the control MRI examination 1 month later (Fig. 2a–c).