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European Radiology

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01-02-2012 | Nuclear Medicine

MRI-based motion correction of thoracic PET: initial comparison of acquisition protocols and correction strategies suitable for simultaneous PET/MRI systems

Authors: Nikolaos Dikaios, David Izquierdo-Garcia, Martin J. Graves, Venkatesh Mani, Zahi A. Fayad, Tim D. Fryer

Published in: European Radiology | Issue 2/2012

Abstract

Objectives

Magnetic resonance imaging (MRI) acquired on equipment capable of simultaneous MRI and positron emission tomography (PET) could potentially provide the gold standard method for motion correction of PET. To assess the latter, in this study we compared fast 2D and 3D MRI of the torso and used deformation parameters from real MRI data to correct simulated PET data for respiratory motion.

Methods

PET sinogram data were simulated using SimSET from a 4D pseudo-PET image series created by segmenting MR images acquired over a respiratory cycle. Motion-corrected PET images were produced using post-reconstruction registration (PRR) and motion-compensated image reconstruction (MCIR).

Results

MRI-based motion correction improved PET image quality at the lung-liver and lung-spleen boundaries and in the heart but little improvement was obtained where MRI contrast was low. The root mean square error in SUV units per voxel compared to a motion-free image was reduced from 0.0271 (no motion correction) to 0.0264 (PRR) and 0.0250 (MCIR).

Conclusions

Motion correction using MRI can improve thoracic PET images but there are limitations due to the quality of fast MRI.

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Title: MRI-based motion correction of thoracic PET: initial comparison of acquisition protocols and correction strategies suitable for simultaneous PET/MRI systems
Authors: Nikolaos Dikaios
David Izquierdo-Garcia
Martin J. Graves
Venkatesh Mani
Zahi A. Fayad
Tim D. Fryer
Publication date: 01-02-2012
Publisher: Springer-Verlag
Published in: European Radiology / Issue 2/2012
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-011-2274-4

At a glance: The STEP trials

Springer Medicine

MRI-based motion correction of thoracic PET: initial comparison of acquisition protocols and correction strategies suitable for simultaneous PET/MRI systems

Abstract

Objectives

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

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