Skip to main content
Top
Published in: European Radiology 9/2017

01-09-2017 | Musculoskeletal

MRI assessment of bone marrow oedema in the sacroiliac joints of patients with spondyloarthritis: is the SPAIR T2w technique comparable to STIR?

Authors: Vitor Faeda Dalto, Rodrigo Luppino Assad, Michel Daoud Crema, Paulo Louzada-Junior, Marcello Henrique Nogueira-Barbosa

Published in: European Radiology | Issue 9/2017

Login to get access

Abstract

Objective

To compare short tau inversion-recovery (STIR) with another fat saturation method in the assessment of sacroiliac joint inflammation.

Methods

This prospective cross-sectional study comprised 76 spondyloarthritis (SpA) patients who underwent magnetic resonance imaging of the sacroiliac joints in a 1.5-T scanner, using STIR, spectral attenuated inversion recovery (SPAIR) T2w and spectral presaturation with inversion recovery (SPIR) T1w post-contrast sequences.
Two independent readers (R1 and R2) assessed the images using the Spondyloarthritis Research Consortium of Canada (SPARCC) score. We assessed agreement of the SPARCC scores for SPAIR T2w and STIR with that for T1 SPIR post-contrast (reference standard) using the St. Laurent coefficient. We evaluated each sequence using the concordance correlation coefficient (CCC).

Results

We observed a strong agreement between STIR and SPAIR T2w sequences. Lin’s CCC was 0.94 for R1 and 0.84 for R2 for STIR and 0.94 for R1 and 0.84 for R2 for SPAIR. The interobserver evaluation revealed a good CCC of 0.79 for SPAIR and 0.78 for STIR.

Conclusion

STIR technique and SPAIR T2w sequence showed high agreement in the evaluation of sacroiliac joint subchondral bone marrow oedema in patients with SpA. SPAIR T2w may be an alternative to the STIR sequence for this purpose.

Key points

There are no studies evaluating which fat saturation technique should be used.
SPAIR T2w may be an alternative to STIR for sacroiliac joint evaluation.
The study will lead to changes in guidelines for spondyloarthritis.
Literature
1.
go back to reference Rudwaleit M, van der Heijde D, Landewé R et al (2009) The development of Assessment of SpondyloArthritis International Society classification criteria for axial spondyloarthritis (part II): Validation and final selection. Ann Rheum Dis 68:777–783CrossRefPubMed Rudwaleit M, van der Heijde D, Landewé R et al (2009) The development of Assessment of SpondyloArthritis International Society classification criteria for axial spondyloarthritis (part II): Validation and final selection. Ann Rheum Dis 68:777–783CrossRefPubMed
2.
go back to reference Rudwaleit M, van der Heijde D, Landewé R et al (2011) The development of Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritis. Ann Rheum Dis 70:25–31CrossRefPubMed Rudwaleit M, van der Heijde D, Landewé R et al (2011) The development of Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritis. Ann Rheum Dis 70:25–31CrossRefPubMed
4.
go back to reference Van der Linden S, Valkenburg HA, Cats A (1984) Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 27:361–368CrossRefPubMed Van der Linden S, Valkenburg HA, Cats A (1984) Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 27:361–368CrossRefPubMed
5.
go back to reference Chary-Valckenaere I, d’Agostino MA, Loeuille D (2011) Role for imaging studies in ankylosing spondylitis. Joint Bone Spine 78:138–143CrossRefPubMed Chary-Valckenaere I, d’Agostino MA, Loeuille D (2011) Role for imaging studies in ankylosing spondylitis. Joint Bone Spine 78:138–143CrossRefPubMed
6.
go back to reference Rudwaleit M, Landewé R, van der Heijde D et al (2009) The development of Assessment of SpondyloArthritis International Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal. Ann Rheum Dis 68:770–776CrossRefPubMed Rudwaleit M, Landewé R, van der Heijde D et al (2009) The development of Assessment of SpondyloArthritis International Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal. Ann Rheum Dis 68:770–776CrossRefPubMed
7.
go back to reference Sieper J, Rudwaleit M, Baraliakos X et al (2009) The Assessment of SpondyloArthritis International Society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis 68:ii1–ii44PubMed Sieper J, Rudwaleit M, Baraliakos X et al (2009) The Assessment of SpondyloArthritis International Society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis 68:ii1–ii44PubMed
9.
go back to reference Weber U, Østergaard M, Lambert RG et al (2011) The impact of MRI on the clinical management of inflammatory arthritides. Skelet Radiol 40:1153–1173CrossRef Weber U, Østergaard M, Lambert RG et al (2011) The impact of MRI on the clinical management of inflammatory arthritides. Skelet Radiol 40:1153–1173CrossRef
10.
go back to reference Delfaut EM, Beltran J, Johnson G et al (1999) Fat suppression in MR imaging techniques and pitfalls. RadioGraphics 19:373–382CrossRefPubMed Delfaut EM, Beltran J, Johnson G et al (1999) Fat suppression in MR imaging techniques and pitfalls. RadioGraphics 19:373–382CrossRefPubMed
11.
go back to reference van Onna M, van Tubergen A, van der Heijde D et al (2014) Gadolinium contrast-enhanced MRI sequence does not have an incremental value in the assessment of sacroiliitis in patients with early inflammatory back pain by using MRI in combination with pelvic radiographs: a 2-year follow-up study. Clin Exp Rheumatol 32:225–230PubMed van Onna M, van Tubergen A, van der Heijde D et al (2014) Gadolinium contrast-enhanced MRI sequence does not have an incremental value in the assessment of sacroiliitis in patients with early inflammatory back pain by using MRI in combination with pelvic radiographs: a 2-year follow-up study. Clin Exp Rheumatol 32:225–230PubMed
12.
go back to reference Althoff CE, Feist E, Burova E et al (2009) Magnetic resonance imaging of active sacroiliitis: do we really need gadolinium? Eur J Radiol 71:232–236CrossRefPubMed Althoff CE, Feist E, Burova E et al (2009) Magnetic resonance imaging of active sacroiliitis: do we really need gadolinium? Eur J Radiol 71:232–236CrossRefPubMed
13.
go back to reference Lukas C, Landewé R, Sieper J et al (2009) Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis. Assessment of SpondyloArthritis international Society. Ann Rheum Dis 68:18–24CrossRefPubMed Lukas C, Landewé R, Sieper J et al (2009) Development of an ASAS-endorsed disease activity score (ASDAS) in patients with ankylosing spondylitis. Assessment of SpondyloArthritis international Society. Ann Rheum Dis 68:18–24CrossRefPubMed
14.
go back to reference Maksymowych WP, Inman RD, Salonen D et al (2005) Spondyloarthritis Research Consortium of Canada magnetic resonance imaging index for assessment of sacroiliac joint inflammation in ankylosing spondylitis. Arthritis Rheum 53:703–709CrossRefPubMed Maksymowych WP, Inman RD, Salonen D et al (2005) Spondyloarthritis Research Consortium of Canada magnetic resonance imaging index for assessment of sacroiliac joint inflammation in ankylosing spondylitis. Arthritis Rheum 53:703–709CrossRefPubMed
15.
go back to reference Maksymowych W, Dhillon SS, Chiowchanwisawakit P et al (2009) Development and validation of web-based training modules for systematic evaluation of active inflammatory lesions in the spine and sacroiliac joints in spondyloarthritis. J Rheumatol 36:48–57 Maksymowych W, Dhillon SS, Chiowchanwisawakit P et al (2009) Development and validation of web-based training modules for systematic evaluation of active inflammatory lesions in the spine and sacroiliac joints in spondyloarthritis. J Rheumatol 36:48–57
16.
go back to reference Lin LI (1989) A concordance correlation coefficient to evaluate reproducibility. Biometrics 45:255–268CrossRefPubMed Lin LI (1989) A concordance correlation coefficient to evaluate reproducibility. Biometrics 45:255–268CrossRefPubMed
17.
go back to reference St Laurent RT (1998) Evaluating agreement with a gold standard in method comparison studies. Biometrics 54:537–545CrossRefPubMed St Laurent RT (1998) Evaluating agreement with a gold standard in method comparison studies. Biometrics 54:537–545CrossRefPubMed
18.
go back to reference Del Grande F, Santini F, Herzka DA et al (2014) Fat-suppression techniques for 3-T MR imaging of the musculoskeletal system. Radiographics 34:217–233CrossRefPubMedPubMedCentral Del Grande F, Santini F, Herzka DA et al (2014) Fat-suppression techniques for 3-T MR imaging of the musculoskeletal system. Radiographics 34:217–233CrossRefPubMedPubMedCentral
19.
go back to reference Rudwaleit M, Jurik AG, Hermann KG et al (2009) Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group. Ann Rheum Dis 68:1520–1527CrossRefPubMed Rudwaleit M, Jurik AG, Hermann KG et al (2009) Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group. Ann Rheum Dis 68:1520–1527CrossRefPubMed
20.
go back to reference Navallas M, Ares J, Beltrán B et al (2013) Sacroiliitis associated with axial spondyloarthropathy: new concepts and latest trends. Radiographics 33:933–956CrossRefPubMed Navallas M, Ares J, Beltrán B et al (2013) Sacroiliitis associated with axial spondyloarthropathy: new concepts and latest trends. Radiographics 33:933–956CrossRefPubMed
21.
go back to reference Bydder GM, Pennock JM, Steiner RE et al (1985) The short TI inversion recovery sequence--an approach to MR imaging of the abdomen. Magn Reson Imaging 3:251–254CrossRefPubMed Bydder GM, Pennock JM, Steiner RE et al (1985) The short TI inversion recovery sequence--an approach to MR imaging of the abdomen. Magn Reson Imaging 3:251–254CrossRefPubMed
22.
go back to reference Yu H, Reeder SB, Shimakawa A et al (2005) Field map estimation with a region growing scheme for iterative 3-point water-fat decomposition. Magn Reson Med 54:1032–1039CrossRefPubMed Yu H, Reeder SB, Shimakawa A et al (2005) Field map estimation with a region growing scheme for iterative 3-point water-fat decomposition. Magn Reson Med 54:1032–1039CrossRefPubMed
23.
go back to reference Giraudo C, Magnaldi S, Weber M et al (2016) Optimizing the MRI protocol of the sacroiliac joints in Spondyloarthritis: which para-axial sequence should be used? Eur Radiol 26:122–129CrossRefPubMed Giraudo C, Magnaldi S, Weber M et al (2016) Optimizing the MRI protocol of the sacroiliac joints in Spondyloarthritis: which para-axial sequence should be used? Eur Radiol 26:122–129CrossRefPubMed
Metadata
Title
MRI assessment of bone marrow oedema in the sacroiliac joints of patients with spondyloarthritis: is the SPAIR T2w technique comparable to STIR?
Authors
Vitor Faeda Dalto
Rodrigo Luppino Assad
Michel Daoud Crema
Paulo Louzada-Junior
Marcello Henrique Nogueira-Barbosa
Publication date
01-09-2017
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 9/2017
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-017-4746-7

Other articles of this Issue 9/2017

European Radiology 9/2017 Go to the issue