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Clinical Autonomic Research
Published in: Clinical Autonomic Research 6/2023

11-09-2023 | Letter to the Editor

Mortality risk factors in newly diagnosed diabetic cardiac autonomic neuropathy

Authors: Bruce A. Chase, Sylwia Pocica, Roberta Frigerio, Katerina Markopoulou, Demetrius M. Maraganore, Navamon Aunaetitrakul, Alexander Epshteyn, Alexandru C. Barboi

Published in: Clinical Autonomic Research | Issue 6/2023

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Excerpt

Cardiac autonomic neuropathy (CAN) diagnosis is based on clinical symptoms and supported by noninvasive autonomic reflex tests that establish extent and severity of involvement [1, 2]. CAN is associated with increased mortality [3], cardiovascular disease [4], and chronic kidney disease [5]. If its clinical, genetic, and comorbidity risk factors [6‐8] contribute to pathophysiological processes causing its progression, they may also be mortality risk factors. To inform design of interventions that may reduce mortality in CAN patients living with diabetes, we asked whether genetic variants, clinical attributes, and autonomic testing findings present at the time of CAN diagnosis are associated with increased mortality. …
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Literature
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Metadata
Title
Mortality risk factors in newly diagnosed diabetic cardiac autonomic neuropathy
Authors
Bruce A. Chase
Sylwia Pocica
Roberta Frigerio
Katerina Markopoulou
Demetrius M. Maraganore
Navamon Aunaetitrakul
Alexander Epshteyn
Alexandru C. Barboi
Publication date
11-09-2023
Publisher
Springer Berlin Heidelberg
Published in
Clinical Autonomic Research / Issue 6/2023
Print ISSN: 0959-9851
Electronic ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-023-00975-5

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