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Published in: Archives of Orthopaedic and Trauma Surgery 1/2019

01-01-2019 | Trauma Surgery

Mortality, complication, and fusion rates of patients with odontoid fracture: the impact of age and comorbidities in 204 cases

Authors: Yann Philippe Charles, Yves Ntilikina, Benjamin Blondel, Stéphane Fuentes, Jérémy Allia, Nicolas Bronsard, Maxime Lleu, Benjamin Nicot, Vincent Challier, Joël Godard, Pascal Kouyoumdjian, Nicolas Lonjon, Paulo Marinho, Julien Berthiller, Eurico Freitas, Cédric Barrey

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 1/2019

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Abstract

Purpose

The French Society of Spine Surgery (SFCR) conducted a prospective epidemiologic multicenter study. The purpose was to investigate mortality, complication, and fusion rates in patients with odontoid fracture, depending on age, comorbidities, fracture type, and treatment.

Methods

Out of 204 patients, 60 were ≤ 70 years and 144 were > 70 years. Demographic data, comorbidities, treatment types and complications (general medical, infectious, neurologic, and mechanical), and death were registered within the first year. Fractures were classified according to Anderson–D’Alonzo and Roy–Camille on the initial CT. A 1-year follow-up CT was available in 144 patients to evaluate fracture consolidation.

Results

Type II and oblique-posterior fractures were the most frequent patterns. The treatment was conservative in 52.5% and surgical in 47.5%. The mortality rate in patients ≤ 70 was 3.3% and 16.7% in patients > 70 years (p = 0.0002). Fracture pattern and treatment type did not influence mortality. General medical complications were significantly more frequent > 70 years (p = 0.021) and after surgical treatment (p = 0.028). Neurologic complications occurred in 0.5%, postoperative infections in 2.0%, and implant-related mechanical complications in 10.3% (associated with pseudarthrosis). Fracture fusion was observed in 93.5% of patients ≤ 70 years and in 62.5% >70 years (p < 0.0001). Pseudarthrosis was present in 31.5% of oblique-posterior fractures and in 24.3% after conservative treatment.

Conclusions

Age and comorbidities influenced mortality and medical complication rates most regardless of fracture type and treatment choice. Pseudarthrosis represented the main complication, which increased with age. Pseudarthrosis was most frequent in type II and oblique-posterior fractures after conservative treatment.
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Metadata
Title
Mortality, complication, and fusion rates of patients with odontoid fracture: the impact of age and comorbidities in 204 cases
Authors
Yann Philippe Charles
Yves Ntilikina
Benjamin Blondel
Stéphane Fuentes
Jérémy Allia
Nicolas Bronsard
Maxime Lleu
Benjamin Nicot
Vincent Challier
Joël Godard
Pascal Kouyoumdjian
Nicolas Lonjon
Paulo Marinho
Julien Berthiller
Eurico Freitas
Cédric Barrey
Publication date
01-01-2019
Publisher
Springer Berlin Heidelberg
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 1/2019
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-018-3050-6

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