Top

Social Psychiatry and Psychiatric Epidemiology

Published in:

01-10-2011 | Original Paper

Mortality and causes of death of acute and transient psychotic disorders

Authors: Augusto C. Castagnini, Aksel Bertelsen

Published in: Social Psychiatry and Psychiatric Epidemiology | Issue 10/2011

Abstract

Background

Little is known about mortality associated with acute transient psychoses. This paper examines mortality and causes of death of ICD-10 F23 ‘Acute and transient psychotic disorders’ (ATPD).

Method

Data from all subjects aged over 15 years who were enrolled in 1996 in the Danish psychiatric register with a first-admission diagnosis of ATPD were linked to the national register of causes of death. The standardized mortality ratio (SMR) for overall mortality and specific categories were calculated.

Results

Over the period 1996–2001, 87 (17.3%) of 503 patients with ATPD had died, accounting for a mortality rate of 35.3 per 1,000 person/years. The SMR for all causes (2.9), natural causes (2.5), and unnatural causes (9.2) were significantly increased. Suicide had the greatest SMR (30.9).

Conclusions

These findings argue for excess mortality of ATPD particularly from suicide.

World Health Organization (1992) The ICD-10 classification of mental and behavioural disorders. Clinical descriptions and diagnostic guidelines. WHO, Geneva

Weibel H, Metzger JY (2005) Psychoses délirantes aiguës. EMC Psychiatr 21:40–61CrossRef

Leonhard K (1957) Aufteilung der endogenen Psychosen (The classification of endogenous psychoses, Irvington, New York, 1979). Akademie Verlag, Jena

Strömgren E (1974) Psychogenic psychoses. In: Hirsh RS, Shepherd M (eds) Themes and variations in European psychiatry. Wright, Bristol, pp 97–117

Langfeldt G (1939) The schizophreniform states. Munksgaard, Copenhagen

Mojtbai R (2005) Acute and transient psychotic disorders and brief psychotic disorder. In: Kaplan VA, Sadock BJ (eds) Comprehensive textbook of psychiatry (8th edn). Lippincott Williams & Wilkins, Philadelphia, pp 1512–1522

Jørgensen P, Bennedsen B, Christensen J, Hyllested A (1997) Acute and transient psychotic disorders: a 1-year follow-up study. Acta Psychiatr Scand 96:150–154PubMedCrossRef

Das SK, Malhotra S, Basu D (1999) Family study of acute and transient psychotic disorders: comparison with schizophrenia. Soc Psychiatry Psychiatr Epidemiol 34:328–332PubMedCrossRef

Marneros A, Pillmann F (2004) Acute and transient psychoses. Cambridge University Press, CambridgeCrossRef

10.

Castagnini A, Bertelsen A, Berrios GE (2008) Incidence and diagnostic stability of ICD-10 acute and transient psychotic disorders. Compr Psychiatry 49:255–261PubMedCrossRef

11.

Singh SP, Burns T, Amin S, Jones PB, Harrison G (2004) Acute and transient psychotic disorders: precursors, epidemiology, course and outcome. Br J Psychiatry 185:452–459PubMedCrossRef

12.

Reay R, Mitford E, McCabe K, Paxton R, Turkington D (2009) Incidence and diagnostic diversity in first-episode psychosis. Acta Psychiatr Scand 121:315–319PubMedCrossRef

13.

Jäger MDM, Hintermayr M, Bottlender R, Strauss A, Möller HJ (2003) Course and outcome of first-admitted patients with acute and transient psychotic disorders (ICD-10: F23). Focus on relapses and social adjustment. Eur Arch Psychiatry Clin Neurosci 253:209–215CrossRef

14.

Suda K, Hayashi N, Hiraga M (2005) Predicting features of later development of schizophrenia among patients with acute and transient psychotic disorder. Psychiatry Clin Neurosci 59:146–150PubMedCrossRef

15.

Jørgensen P, Mortensen PB (1990) Reactive psychosis and mortality. Acta Psychiatr Scand 81:277–279PubMedCrossRef

16.

Jørgensen P, Mortensen PB (1992) Causes of death in reactive psychosis. Acta Psychiatr Scand 85:351–353PubMedCrossRef

17.

Munk-Jørgensen P, Mortensen PB (1997) The Danish psychiatric central register. Dan Med Bull 44:82–84PubMed

18.

Juel K, Helweg-Larsen K (1999) The Danish registers of causes of death. Dan Med Bull 46:354–357PubMed

19.

Breslow NE, Day NE (1987) Statistical methods in cancer research. IARC Scientific Publications, Lyon

20.

Juul S (1984) Programmer til overlevelses beregninger. Aarhus Univerisitetsforlage, Aarhus

21.

Kørner A, Lopez AG, Andersen PK, Kessing LV (2009) Acute and transient psychosis in old age and the subsequent risk of dementia: a nationwide register-based study. Geriatr Gerontol Int 9:62–68PubMedCrossRef

22.

Bär KJ, Koschke M, Boettger MK, Berger S, Kabisch A, Sauer H, Voss A, Yeragani VK (2007) Acute psychosis leads to increased QT variability in patients suffering schizophrenia. Schizophr Res 95:115–123PubMedCrossRef

23.

Jäger MDM, Riedel M, Möller HJ (2007) Akute vorübergehende psychotische Störungen (ICD-10: F23). Empirische Befunde und Implikationen für die Therapie. Nervenarzt 78:749–752CrossRef

24.

Newcomer JW (2007) Antipsychotic medications: metabolic and cardiovascular risk. J Clin Psychiatry 68(Suppl 4):8–13PubMed

25.

Bertelsen M, Jeppesen P, Petersen L, Thorup A, Ohlenschlaeger J, le Quach P, Christensen TO, Krarup G, Jorgensen P, Nordentoft M (2007) Suicidal behaviour and mortality in first-episode psychosis: the OPUS trial. Br J Psychiatry 191(Suppl 51):140–146CrossRef

26.

Qui P, Nordentoft M (2004) Suicide risk in relation to psychiatric hospitalization. Arch Gen Psychiatry 62:427–432

27.

McGorry P, Chanen A, McCarthy E, Van Riel R, McKenzie D, Sing B (1991) Post-traumatic stress disorder following recent onset psychosis: an unrecognized post-psychotic syndrome. J Nerv Ment Dis 179:253–258PubMedCrossRef

28.

Jackson C, Knott C, Skeate A, Birchwood M (2004) The trauma of first episode psychosis: the role of cognitive mediation. Aus NZ J Psychiatry 38:233–327CrossRef

29.

Craig TJ, Ye Q, Bromet EJ (2006) Mortality among first-admission patients with psychosis. Compr Psychiatry 47:246–251PubMedCrossRef

30.

Pillmann F, Balzuweit S, Haring A, Bloink R, Marneros A (2003) Suicidal behavior in acute and transient psychotic disorders. Psychiatry Res 117:199–209PubMedCrossRef

31.

Löffler W, Häfner H, Fätkenheurer B, Maurer K, Riecher-Rössler A, Lützhøft J, Skadhede S, Munk-Jørgensen P, Strömgren E (1994) Validation of Danish case register diagnosis of schizophrenia. Acta Psychiatr Scand 90:196–201PubMedCrossRef

Title: Mortality and causes of death of acute and transient psychotic disorders
Authors: Augusto C. Castagnini
Aksel Bertelsen
Publication date: 01-10-2011
Publisher: Springer-Verlag
Published in: Social Psychiatry and Psychiatric Epidemiology / Issue 10/2011
Print ISSN: 0933-7954
Electronic ISSN: 1433-9285
DOI: https://doi.org/10.1007/s00127-010-0276-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Mortality and causes of death of acute and transient psychotic disorders

Abstract

Background

Method

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Method

Results

Conclusions

Please log in to get access to this content

Other articles of this Issue 10/2011

What makes community psychiatric nurses label non-psychotic chronic patients as ‘difficult’: patient, professional, treatment and social variables

Attempted suicide in mental disorders in young adulthood

Demands, control, supportive relationships and well-being amongst British mental health workers

Chronic somatic complaints in adolescents: prevalence, predictive validity of the parent reports, and associations with social class, health status, and psychosocial distress

Changes in religious beliefs and the relation of religiosity to posttraumatic stress and life satisfaction after a natural disaster

Anxiety, mood, and substance use disorders in United States African-American public housing residents