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Published in: BMC Anesthesiology 1/2020

Open Access 01-12-2020 | Morphine | Research article

A randomized controlled trial evaluating the impact of selective axillary nerve block after arthroscopic subacromial decompression

Authors: Christian Rothe, Jørgen Lund, Morten Troels Jenstrup, Christian Steen-Hansen, Lars Hyldborg Lundstrøm, Asger Mølgaard Andreasen, Kai Henrik Wiborg Lange

Published in: BMC Anesthesiology | Issue 1/2020

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Abstract

Background

The sensory innervation of the shoulder is complex and there are variations in the branching patterns of the sensory fibres. Articular branches from the axillary nerve to the subacromial bursa are described in more than 50% of investigated shoulders but the isolated contribution of sensory input from the axillary nerve has never been investigated clinically.
We hypothesized that a selective block of the axillary nerve would reduce morphine consumption and pain after arthroscopic subacromial decompression.

Methods

We included 60 patients in a randomized, blinded, placebo-controlled study. Patients were randomized to a preoperative selective ultrasound-guided axillary nerve block with 20 mL ropivacaine (7.5 mg/mL) or 20 mL saline. Primary outcome was intravenous morphine consumption 0–4 h postoperatively. Secondary outcome was postoperative pain evaluated by a visual analogue scale (VAS) score (0–100).

Results

We analysed data from 50 patients and found no significant difference in 0–4 h postoperative morphine consumption between the two groups (ropivacaine 14 mg, placebo 18 mg (P = 0.12)). There was a reduction in postoperative pain: VAS 0–4 h (area under the curve) (ropivacaine 135, placebo 182 (P = 0.03)), VAS after 8 h (ropivacaine 9, placebo 20 (P = 0.01)) and VAS after 24 h (ropivacaine 7, placebo 18 (P = 0.04)). Eight out of 19 patients with a successful selective axillary nerve block needed an interscalene brachial plexus escape block.

Conclusions

Selective block of the axillary nerve has some pain relieving effect, but in this setting the effect was unpredictable, variable and far from sufficient in a large proportion of the patients.

Trial registration

ClinicalTrials.gov (NCT01463865). Registered: November 1, 2011.
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Metadata
Title
A randomized controlled trial evaluating the impact of selective axillary nerve block after arthroscopic subacromial decompression
Authors
Christian Rothe
Jørgen Lund
Morten Troels Jenstrup
Christian Steen-Hansen
Lars Hyldborg Lundstrøm
Asger Mølgaard Andreasen
Kai Henrik Wiborg Lange
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Anesthesiology / Issue 1/2020
Electronic ISSN: 1471-2253
DOI
https://doi.org/10.1186/s12871-020-0952-y

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