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Published in: Osteoporosis International 1/2017

01-01-2017 | Original Article

More-than-minimal-trauma fractures are associated with low bone density: an 8-year prospective study

Authors: L. Pereira, D. Bliuc, P. Stanford, J. A. Eisman, J. R. Center

Published in: Osteoporosis International | Issue 1/2017

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Abstract

Summary

Few studies have examined the relationship between more-than-minimal-trauma fractures and bone density. This study demonstrated that more-than-minimal-trauma fractures are associated with lower bone density similar to that seen in minimal trauma fractures. Men and women over 50 years with a more-than-minimal-trauma fracture should be investigated to exclude low bone density.

Introduction

The aim of this study was to assess the prevalence and predictors of low bone density in men and women with more-than-minimal-trauma fractures.

Methods

In an Australian hospital, 630 community-dwelling men and women, 20 years of age or older, sustained a fracture due to more-than-minimal-trauma (force greater than a fall from standing height but less than high trauma). We studied 349 individuals who agreed to have a bone mineral density (BMD) scan. These participants were compared with 472 men and women with minimal trauma fractures.

Results

Men and women with more-than-minimal-trauma fractures had significantly lower bone density than expected for their age, gender and weight (Z-scorespine = −0.4 SD, 95 % confidence interval (CI), −0.5 to −0.3; Z-scorehip = −0.5 SD, 95 % CI, −0.6 to −0.4). Almost 1 in 4 of those over 50 years of age had osteoporosis by BMD criteria. The independent predictors of low bone density (T-score <−2.0 SD) were age equal to or over 50 years (odds ratio (OR) = 5.97, 95 % CI, 3.34 to 10.65), low body weight <20 kg/m2 (OR = 3.44, 95 % CI, 1.32 to 8.94), a prior minimal trauma fracture (OR = 2.76, 95 % CI, 1.17–6.52) and in those over 50 years of age, an osteoporosis-associated condition (OR = 4.51, 95 % CI, 1.69 to 12.06). Men and women with more-than-minimal-trauma fractures had similar bone density (Z-score) compared to those with minimal trauma fractures.

Conclusions

Men and women over 50 years with a more-than-minimal-trauma fracture, especially those with low body weight, prior minimal trauma fracture or an osteoporosis-associated condition, should be investigated to exclude low bone density and its associated risk of subsequent fractures.
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Metadata
Title
More-than-minimal-trauma fractures are associated with low bone density: an 8-year prospective study
Authors
L. Pereira
D. Bliuc
P. Stanford
J. A. Eisman
J. R. Center
Publication date
01-01-2017
Publisher
Springer London
Published in
Osteoporosis International / Issue 1/2017
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-016-3739-8

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