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01-06-2019 | Mononucleosis | Case Report

Hypertrophic chronic pachymeningitis associated with Epstein-Barr virus reactivation: a case report

Authors: Raffaele Nardone, Francesco Brigo, Markus Covi, Luca Carnicelli, Francesca Caleri, Hannes Tischler, Larissa Hauer, Johann Sellner

Published in: Journal of NeuroVirology | Issue 3/2019

Abstract

Hypertrophic pachymeningitis is a rare inflammatory condition characterized by the thickening of the dura mater. We describe a patient who presented with intractable headache and complex cranial nerve palsy. Hypertrophy of the frontal dura was accompanied by pleocytosis and detection of Epstein-Barr virus (EBV) by PCR in cerebrospinal fluid. Clinical symptoms gradually improved after acyclovir and corticosteroid treatment, whereas dural pathology remained unchanged on neuroimaging. This case points at an expansion of the spectrum of neurological manifestations for EBV.

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Title: Hypertrophic chronic pachymeningitis associated with Epstein-Barr virus reactivation: a case report
Authors: Raffaele Nardone
Francesco Brigo
Markus Covi
Luca Carnicelli
Francesca Caleri
Hannes Tischler
Larissa Hauer
Johann Sellner
Publication date: 01-06-2019
Publisher: Springer International Publishing
Keywords: Mononucleosis
Epstein-Barr Virus
Polymerase Chain Reaction
Headache
Mononucleosis
Published in: Journal of NeuroVirology / Issue 3/2019
Print ISSN: 1355-0284
Electronic ISSN: 1538-2443
DOI: https://doi.org/10.1007/s13365-019-00731-4

At a glance: The STEP trials

Springer Medicine

Hypertrophic chronic pachymeningitis associated with Epstein-Barr virus reactivation: a case report

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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