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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 5/2018

01-05-2018 | Original Article

Molecular Epidemiology of Rotavirus Strains in Under Five Children

Authors: Yunus Bulut, Gülgün Yenişehirli, Rıza Durmaz

Published in: Indian Journal of Pediatrics | Issue 5/2018

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Abstract

Objectives

To determine the prevalence and genotype distribution of rotaviruses in children presenting to authors’ hospital in Middle Black Sea region of Turkey. The results may supply important information about vaccine studies in Turkey.

Methods

Rotavirus antigen was detected by latex agglutination test and rotavirus RNA was detected by RT-PCR test. On the other hand, rotavirus positive samples were genotyped by semi-nested multiplex polymerase chain reaction.

Results

The highest rate of rotavirus positivity (46.9%) was observed among children in the 13 to 24 mo age group. All the positive-strains were in G1–4, G8–9, P [4], P [8], and P [9] genotypes. The most common G and P combination in present study was G9P[8] (n = 24, 28.9%).

Conclusions

The present results indicated that the most prevalent genotypes were G1, G9, P8, G9P[8] and G1P[8] in authors’ region. Rotavirus vaccines used in this region must include mainly these genotypes.
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Metadata
Title
Molecular Epidemiology of Rotavirus Strains in Under Five Children
Authors
Yunus Bulut
Gülgün Yenişehirli
Rıza Durmaz
Publication date
01-05-2018
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 5/2018
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-017-2540-9

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