Published in:
Open Access
01-10-2012 | Oral presentation
Molecular diagnosis for screening and elimination of malaria: performance of the first commercially-available malaria LAMP test
Authors:
Iveth J González, Spencer Polley, Heidi Hopkins, Colin Sutherland, Yasuyoshi Mori, Mark Perkins, David Bell
Published in:
Malaria Journal
|
Special Issue 1/2012
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Excerpt
The ability to screen for asymptomatic malaria infection at a field level is increasingly recognized as a key strategy in malaria elimination campaigns. However, molecular methods necessary to detect very low parasite density infections, such as PCR, are restricted to reference-level laboratories and require considerable training to perform. To be effective, such techniques must be close enough to the positive cases to enable rapid treatment. Loop-mediated isothermal DNA amplification (LAMP) is highly sensitive and specific, faster than PCR, requires minimal processing and instrumentation, and allows result detection with the naked eye. …