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Published in: Malaria Journal 1/2012

Open Access 01-10-2012 | Oral presentation

Molecular diagnosis for screening and elimination of malaria: performance of the first commercially-available malaria LAMP test

Authors: Iveth J González, Spencer Polley, Heidi Hopkins, Colin Sutherland, Yasuyoshi Mori, Mark Perkins, David Bell

Published in: Malaria Journal | Special Issue 1/2012

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Excerpt

The ability to screen for asymptomatic malaria infection at a field level is increasingly recognized as a key strategy in malaria elimination campaigns. However, molecular methods necessary to detect very low parasite density infections, such as PCR, are restricted to reference-level laboratories and require considerable training to perform. To be effective, such techniques must be close enough to the positive cases to enable rapid treatment. Loop-mediated isothermal DNA amplification (LAMP) is highly sensitive and specific, faster than PCR, requires minimal processing and instrumentation, and allows result detection with the naked eye. …
Metadata
Title
Molecular diagnosis for screening and elimination of malaria: performance of the first commercially-available malaria LAMP test
Authors
Iveth J González
Spencer Polley
Heidi Hopkins
Colin Sutherland
Yasuyoshi Mori
Mark Perkins
David Bell
Publication date
01-10-2012
Publisher
BioMed Central
Published in
Malaria Journal / Issue Special Issue 1/2012
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/1475-2875-11-S1-O30

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