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Open Access 01-12-2009 | Review

Molecular allergology approach to allergic diseases in the paediatric age

Authors: Claudia Alessandri, Danila Zennaro, Alessandra Zaffiro, Adriano Mari

Published in: Italian Journal of Pediatrics | Issue 1/2009

Abstract

Identification, characterization, and purification of allergens are essential for the structural and immunologic studies needed to understand how these molecules induce specific IgE antibody production by the human immune system. Advances in molecular biology techniques have led to the production of recombinant allergens having constant properties, allowing detection of specific IgE directed against different molecular components of an allergenic source. Presence of homologous allergens in different sources is the reason for cross-reaction. Molecule-based diagnostic tools can lead to better interpretation of poly-sensitizations, observed by ST and in vitro tests using allergenic extracts as they were made before. Some examples IgE sensitization to major genuine allergens and panallergens will be presented.

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Title: Molecular allergology approach to allergic diseases in the paediatric age
Authors: Claudia Alessandri
Danila Zennaro
Alessandra Zaffiro
Adriano Mari
Publication date: 01-12-2009
Publisher: BioMed Central
Published in: Italian Journal of Pediatrics / Issue 1/2009
Electronic ISSN: 1824-7288
DOI: https://doi.org/10.1186/1824-7288-35-29

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Molecular allergology approach to allergic diseases in the paediatric age

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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