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Published in: Journal of Medical Case Reports 1/2015

Open Access 01-12-2015 | Case report

Mixed Streptococcus pneumoniae and Streptococcus pyogenes meningitis in an immunocompromised adult patient: a case report

Authors: Clémence Demerle, Vadim Ivanov, Cédric Mercier, Régis Costello, Michel Drancourt

Published in: Journal of Medical Case Reports | Issue 1/2015

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Abstract

Introduction

Community-acquired meningitis is a monomicrobial infection caused by either viruses or bacteria in the vast majority of patients. We report here one exceptional case of a patient with mixed bacterial meningitis due to Streptococcus pneumoniae and Streptococcus pyogenes.

Case presentation

We report the case of a 68-year-old immunocompromised Caucasian man suffering from otitis and then meningitis caused by Streptococcus pneumoniae and Streptococcus pyogenes. Bacteria were undistinguishable by direct microscopic examination of the cerebrospinal fluid. He responded well to treatment with cefotaxime and dexamethasone, with no sequelae observed at the 4-month follow-up.

Conclusions

This first reported case of mixed S. pneumoniae and S. pyogenes meningitis illustrates the life-threatening consequences of barotrauma in immunocompromised patients suffering from otorhinolaryngeal infections.
Literature
1.
go back to reference Thigpen M, Whitney C, Messonnier N, Zell E, Lynfield R, Hadler J, et al. Bacterial meningitis in the United States, 1998–2007. N Eng J Med. 2011;26:2016–25.CrossRef Thigpen M, Whitney C, Messonnier N, Zell E, Lynfield R, Hadler J, et al. Bacterial meningitis in the United States, 1998–2007. N Eng J Med. 2011;26:2016–25.CrossRef
2.
go back to reference Brouwer M, Thwaites G, Tunkel A, Van de Beek D. Dilemmas in the diagnosis of acute community-acquired bacterial meningitis. Lancet. 2012;10:1684–92.CrossRef Brouwer M, Thwaites G, Tunkel A, Van de Beek D. Dilemmas in the diagnosis of acute community-acquired bacterial meningitis. Lancet. 2012;10:1684–92.CrossRef
3.
go back to reference Chaudhuri A, Martin P, Kennedy P, Seaton A, Portegies P, Bojar M, et al. EFNS guideline on the management of community-acquired bacterial meningitis: report of an EFNS Task Force on acute bacterial meningitis in older children and adults. Eur J Neurol. 2008;15:649–59.CrossRefPubMed Chaudhuri A, Martin P, Kennedy P, Seaton A, Portegies P, Bojar M, et al. EFNS guideline on the management of community-acquired bacterial meningitis: report of an EFNS Task Force on acute bacterial meningitis in older children and adults. Eur J Neurol. 2008;15:649–59.CrossRefPubMed
4.
go back to reference Brouwer MC, McIntyre P, Prasad K, Van de Beek D. Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev. 2013;6:CD004405.PubMed Brouwer MC, McIntyre P, Prasad K, Van de Beek D. Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev. 2013;6:CD004405.PubMed
5.
go back to reference Cohen-Bacrie S, Ninove L, Nougairède A, Charrel R, Richet H, Minodier P, et al. Revolutionizing clinical microbiology laboratory organization in hospitals with in situ point-of-care. PLoS One. 2011;6:e22403.CrossRefPubMedPubMedCentral Cohen-Bacrie S, Ninove L, Nougairède A, Charrel R, Richet H, Minodier P, et al. Revolutionizing clinical microbiology laboratory organization in hospitals with in situ point-of-care. PLoS One. 2011;6:e22403.CrossRefPubMedPubMedCentral
6.
go back to reference Marcos MA, Martínez E, Almela M, Mensa J, de Anta MT J. New rapid antigen test for diagnosis of pneumococcal meningitis. Lancet. 2001;357:1499–500.CrossRefPubMed Marcos MA, Martínez E, Almela M, Mensa J, de Anta MT J. New rapid antigen test for diagnosis of pneumococcal meningitis. Lancet. 2001;357:1499–500.CrossRefPubMed
7.
go back to reference Seng P, Drancourt M, Gouriet F, La Scola B, Fournier PE, Rolain JM, et al. Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Clin Infect Dis. 2009;49:543–51.CrossRefPubMed Seng P, Drancourt M, Gouriet F, La Scola B, Fournier PE, Rolain JM, et al. Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Clin Infect Dis. 2009;49:543–51.CrossRefPubMed
8.
go back to reference Lucas MJ, Brouwer MC, Bovenkerk S, Man WK, van der Ende A, van de Beek D. Group A Streptococcal meningitis in adults. J Infect. 2015;71:37–42.CrossRefPubMed Lucas MJ, Brouwer MC, Bovenkerk S, Man WK, van der Ende A, van de Beek D. Group A Streptococcal meningitis in adults. J Infect. 2015;71:37–42.CrossRefPubMed
9.
go back to reference Hagiya H, Otsuka F. Group A streptococcal meningitis in a patient with palmoplantar pustulosis. Intern Med. 2013;52:2675–8.CrossRefPubMed Hagiya H, Otsuka F. Group A streptococcal meningitis in a patient with palmoplantar pustulosis. Intern Med. 2013;52:2675–8.CrossRefPubMed
10.
go back to reference Ulug M, Ulug NC, Celen MK, Geyik MF, Ayaz C. A case of meningitis caused by Streptococcus pyogenes in a previously healthy woman. J Infect Dev Ctries. 2009;1:241–4. Ulug M, Ulug NC, Celen MK, Geyik MF, Ayaz C. A case of meningitis caused by Streptococcus pyogenes in a previously healthy woman. J Infect Dev Ctries. 2009;1:241–4.
11.
go back to reference Zappella N, Barrelet A, Pangon B, Laurent V, Bruneel F. Group A streptococcal meningitis: Streptococcus pneumoniae is not the only one to seep into the CSF fluid leak! Ann Fr Anesth Reanim. 2013;32:811–3.CrossRefPubMed Zappella N, Barrelet A, Pangon B, Laurent V, Bruneel F. Group A streptococcal meningitis: Streptococcus pneumoniae is not the only one to seep into the CSF fluid leak! Ann Fr Anesth Reanim. 2013;32:811–3.CrossRefPubMed
12.
13.
go back to reference Vo-Tan D, Portmann D, Carrat X. From barotrauma otitis to a fulminant meningitis. Rev Laryngol Otol Rhinol (Bord). 2010;131:229–32. Vo-Tan D, Portmann D, Carrat X. From barotrauma otitis to a fulminant meningitis. Rev Laryngol Otol Rhinol (Bord). 2010;131:229–32.
14.
go back to reference Tsiodras S, Samonis G, Keating M, Kontoyiannis D, Dimitrios P. Infection and immunity in chronic lymphocytic leukemia. Mayo Clin Proc. 2000;75:1039–54.CrossRefPubMed Tsiodras S, Samonis G, Keating M, Kontoyiannis D, Dimitrios P. Infection and immunity in chronic lymphocytic leukemia. Mayo Clin Proc. 2000;75:1039–54.CrossRefPubMed
15.
go back to reference Sinisalo M, Vilpo J, Itälä M, Väkeväinen M, Taurio J, Aittoniemi J. Antibody response to 7-valent conjugated pneumococcal vaccine in patients with chronic lymphocytic leukaemia. Vaccine. 2007;26:82–7.CrossRefPubMed Sinisalo M, Vilpo J, Itälä M, Väkeväinen M, Taurio J, Aittoniemi J. Antibody response to 7-valent conjugated pneumococcal vaccine in patients with chronic lymphocytic leukaemia. Vaccine. 2007;26:82–7.CrossRefPubMed
Metadata
Title
Mixed Streptococcus pneumoniae and Streptococcus pyogenes meningitis in an immunocompromised adult patient: a case report
Authors
Clémence Demerle
Vadim Ivanov
Cédric Mercier
Régis Costello
Michel Drancourt
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2015
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-015-0763-9

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