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Journal of Cardiothoracic Surgery

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Open Access 01-12-2020 | Mitral Valve Replacement | Review

Mitral valve re-repair vs replacement following failed initial repair: a systematic review and meta-analysis

Authors: Muthu Veerappan, Prashasth Cheekoty, Faizus Sazzad, Theo Kofidis

Published in: Journal of Cardiothoracic Surgery | Issue 1/2020

Abstract

Background

The optimal treatment strategy following a failed mitral valve repair remains unclear. This study aims to compare and analyse available studies which report the clinical outcomes post mitral valve re-repair (MVr) or replacement (MVR) after a prior mitral valve repair.

Methods

Based on PRISMA guidelines, a literature search was performed utilising PubMed, Cochrane and Scopus databases to identify retrospective cohort studies that reported outcomes of MVr and MVR after a prior mitral valve repair. Data regarding operative mortality, clinical outcomes and complications were extracted, synthesized and meta-analysed where appropriate.

Results

Eight studies with a total cohort of 1632 patients were used. After analysis, no significant differences in the short term and long-term operative mortality, incidence of stroke, congestive heart failure, Grade 1 and Grade 2 mitral regurgitation, requirement of 3rd mitral valve operation and reoperation due bleeding were found between the two groups. However, a slightly higher incidence of postoperative atrial fibrillation (OR: 0.11, CI: 0.02 to 0.17, I² = 0%, p = 0.02) was observed in the MVR group, as compared to the MVr group.

Conclusion

MVr appears to be a viable alternative to MVR for mitral valve reoperation, given that they are associated with similar post-operative outcomes.

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Title: Mitral valve re-repair vs replacement following failed initial repair: a systematic review and meta-analysis
Authors: Muthu Veerappan
Prashasth Cheekoty
Faizus Sazzad
Theo Kofidis
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Mitral Valve Replacement
Mitral Valve Replacement
Mitral Valve Replacement
Published in: Journal of Cardiothoracic Surgery / Issue 1/2020
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-020-01344-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Mitral valve re-repair vs replacement following failed initial repair: a systematic review and meta-analysis

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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